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FABP6 Knockout Cell Lines

Gene: FABP6

Official Full Name: fatty acid binding protein 6provided by HGNC

Gene Summary: This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37920 FABP6 Knockout cell line (HCT 116) Human FABP6 1:2~1:4 Negative Online Inquiry
KO37921 FABP6 Knockout cell line (HEK293) Human FABP6 1:3~1:6 Negative Online Inquiry
KO37922 FABP6 Knockout cell line (A549) Human FABP6 1:3~1:4 Negative Online Inquiry

Background

FABP6 Gene Knockout Cell Lines represent a pivotal advancement for researchers delving into the molecular mechanisms of lipid metabolism and related metabolic disorders. These cell lines are engineered to lack the expression of the fatty acid-binding protein 6 (FABP6), a key player in the transport of long-chain fatty acids and the regulation of metabolic pathways. By employing sophisticated gene-editing techniques, such as CRISPR/Cas9, these knockout cell lines provide scientists with a unique model to study the physiological and pathological roles of FABP6 in various cellular contexts.

The primary function of FABP6 involves facilitating the uptake and intracellular transport of fatty acids. This is crucial for their subsequent oxidation or storage. Using FABP6 gene knockout cell lines, researchers can dissect the intricate pathways involved in lipid signaling and the contribution of these pathways to diseases such as obesity and type 2 diabetes. The absence of FABP6 allows for an unparalleled exploration of compensatory mechanisms within lipid metabolism, making these cell lines valuable for both biochemical assays and high-throughput screening applications.

In terms of scientific importance, FABP6 knockout models are instrumental in providing insights into metabolic syndromes and developing therapeutic strategies for lipid-related disorders. Compared to conventional wild-type cell lines, these knockout models enable a clear understanding of lipid homeostasis without the confounding effects of FABP6, thus presenting a more accurate milieu for experimentation.

Additionally, the unique selling points of FABP6 Gene Knockout Cell Lines extend to their ability to support reproducibility and validation in research findings. Researchers seeking robust platforms for drug discovery and metabolic research will find these cell lines indispensable, as they facilitate precise manipulation of metabolic pathways without the risk of off-target effects.

The value proposition for researchers and clinicians is clear: FABP6 Gene Knockout Cell Lines provide a powerful tool for elucidating metabolic processes and developing targeted therapies in conditions characterized by lipid dysregulation. Our company, with its extensive expertise in genetic engineering and commitment to advancing biological research, is proud to offer these state-of-the-art cell lines, designed specifically to enhance the rigor and applicability of research in metabolic diseases.

Please note that all services are for research use only. Not intended for any clinical use.

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