Gene: FABP5
Official Full Name: fatty acid binding protein 5provided by HGNC
Gene Summary: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00391 | FABP5 Knockout cell line(MDA-MB-231) | Human | FABP5 | 1:2~1:4 | Negative | Online Inquiry |
FABP5 Gene Knockout Cell Lines are specialized laboratory tools developed for researchers investigating the biological role of the fatty acid binding protein 5 (FABP5). These cell lines have been genetically engineered to disrupt the expression of the FABP5 gene, enabling scientists to study the consequences of its absence on cellular metabolism, proliferation, differentiation, and signaling pathways associated with lipid metabolism and various pathologies.
The key mechanism behind FABP5 knockout is the use of advanced CRISPR-Cas9 technology, which allows for precise editing of the genome. By generating cell lines deficient in FABP5, researchers can assess how the lack of this protein influences lipid transport, fatty acid metabolism, and overall cell functionality. This can provide crucial insights into its roles in diseases, such as obesity, diabetes, cancer, and cardiovascular disorders.
The scientific importance of FABP5 Gene Knockout Cell Lines extends to multiple applications in both research and clinical settings. They serve as powerful tools for drug discovery, enabling the screening of therapeutic candidates aimed at modulating lipid signaling pathways. Furthermore, these cell lines contribute to translational research by providing a more accurate model for human diseases and aiding in the understanding of metabolic disorders.
Compared to alternative methods, our FABP5 Gene Knockout Cell Lines offer superior specificity and reliability, yielding reproducible results in experimental protocols. Unlike transient knockdown techniques, our knockout lines support long-term studies, enabling researchers to gather a more comprehensive understanding of FABP5 functions over extended periods.
For researchers, clinicians, and institutions committed to advancing the field of metabolic studies, these FABP5 Gene Knockout Cell Lines represent an invaluable asset. They facilitate groundbreaking research and provide a foundational model to explore therapeutic pathways and disease mechanisms. We stand behind our product, bolstered by our company’s commitment to innovation and excellence in biological products, ensuring that our offerings meet the highest scientific standards.
Please note that all services are for research use only. Not intended for any clinical use.
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