Gene: FABP3
Official Full Name: fatty acid binding protein 3provided by HGNC
Gene Summary: The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09321 | FABP3 Knockout cell line (HeLa) | Human | FABP3 | 1:3~1:6 | Negative | Online Inquiry |
KO09322 | FABP3 Knockout cell line (HEK293) | Human | FABP3 | 1:3~1:6 | Negative | Online Inquiry |
FABP3 Gene Knockout Cell Lines are specifically engineered cell models designed to lack the fatty acid-binding protein 3 (FABP3), a critical component involved in fatty acid metabolism and cellular signaling. These cell lines are instrumental in research endeavors aimed at elucidating the pathways influenced by FABP3, thereby enhancing our understanding of various physiological and pathological processes such as metabolic syndrome, cardiovascular diseases, and cancer.
At the cellular level, FABP3 acts by binding and transporting long-chain fatty acids, which are crucial for energy production and cellular function. By knocking out the FABP3 gene, these cell lines provide researchers with a powerful tool to investigate the impact of fatty acid transport deficiency on cell growth, differentiation, and response to hormonal stimuli. This alteration can lead to pronounced changes in lipid metabolism, making these models invaluable for studying diseases linked to metabolic dysregulation.
The scientific importance of FABP3 gene knockout cell lines extends to both basic research and clinical settings. They serve as a platform for drug discovery efforts, enabling the identification of novel therapeutic targets for metabolic disorders. Additionally, by utilizing these specific cell lines, researchers can conduct in-depth studies into the role of FABP3 in cancer progression, potentially paving the way for innovative cancer treatments.
Compared to alternative models, FABP3 knockout cell lines provide enhanced specificity for examining FABP3-related mechanisms without the confounding effects of other fatty acid-binding proteins. This unique feature allows for more precise observations and interpretations of experimental results, ultimately leading to more robust conclusions.
For researchers and clinicians alike, the value of FABP3 gene knockout cell lines is evident; they enable cutting-edge investigations that could lead to critical breakthroughs in understanding and treating complex diseases. Our company's extensive expertise in the field of genetic engineering and commitment to high-quality biological products ensures that these knockout cell lines are rigorously validated and ready for immediate use in your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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