Gene: EYA2
Official Full Name: EYA transcriptional coactivator and phosphatase 2provided by HGNC
Gene Summary: This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may be post-translationally modified and may play a role in eye development. A similar protein in mice can act as a transcriptional activator. Alternative splicing results in multiple transcript variants, but the full-length natures of all of these variants have not yet been determined. [provided by RefSeq, Jul 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37928 | EYA2 Knockout cell line (HEK293) | Human | EYA2 | 1:3~1:6 | Negative | Online Inquiry |
KO37929 | EYA2 Knockout cell line (A549) | Human | EYA2 | 1:3~1:4 | Negative | Online Inquiry |
EYA2 Gene Knockout Cell Lines are specialized cellular models created through advanced genetic engineering techniques to selectively deactivate the EYA2 gene, which encodes a transcriptional co-activator involved in various developmental and disease processes. By eliminating this gene's expression, these cell lines allow researchers to study the effects of EYA2 loss on cellular functions, signaling pathways, and molecular interactions.
The key function of EYA2 Gene Knockout Cell Lines is to facilitate the exploration of EYA2's role in critical biological processes such as cell differentiation, proliferation, and apoptosis. These cell lines are instrumental in mechanistic studies aimed at understanding the gene's involvement in developmental biology, cancer biology, and regenerative medicine. The knockout approach leads to measurable phenotypic changes, thereby providing insights into the pathogenic mechanisms underlying EYA2-associated diseases.
The scientific importance of EYA2 Gene Knockout Cell Lines is underscored by their broad applications in both research and clinical settings, particularly in understanding ocular development and possible therapeutic interventions for EYA2-related disorders. The use of these specialized cells can accelerate drug discovery and aid in the validation of genetic targets, offering potential pathways for novel treatment options.
Compared to alternatives such as transient knockdown techniques, EYA2 Gene Knockout Cell Lines provide a stable and heritable model system that ensures consistent results for long-term studies. This stability allows researchers to conduct experiments over extended periods, enhancing data reliability and reproducibility.
Researchers and clinicians can greatly benefit from the EYA2 Gene Knockout Cell Lines, as they provide a critical tool for dissecting the biological roles of EYA2 and generating insights into its contributions to health and disease. By investing in these advanced cellular models, users can facilitate discoveries that may lead to groundbreaking therapeutic strategies.
With years of expertise in genetic engineering and cellular biology, our company is dedicated to providing high-quality biological products that empower researchers and clinicians to advance their work. Our EYA2 Gene Knockout Cell Lines are rigorously validated to ensure optimal performance, making them a strategic addition to any laboratory focused on innovative biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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