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ETS2 Knockout Cell Lines

Gene: ETS2

Official Full Name: ETS proto-oncogene 2, transcription factorprovided by HGNC

Gene Summary: This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08869 ETS2 Knockout cell line (HeLa) Human ETS2 1:3~1:6 Negative Online Inquiry
KO08870 ETS2 Knockout cell line (HCT 116) Human ETS2 1:2~1:4 Negative Online Inquiry
KO08871 ETS2 Knockout cell line (HEK293) Human ETS2 1:3~1:6 Negative Online Inquiry
KO08872 ETS2 Knockout cell line (A549) Human ETS2 1:3~1:4 Negative Online Inquiry

Background

ETS2 Gene Knockout Cell Lines are a specialized biological tool designed to facilitate the functional analysis of the ETS2 gene, which encodes a transcription factor involved in numerous cellular processes including cell growth, differentiation, and apoptosis. By generating specific knockout cell lines, researchers can study the absence of ETS2 and its effects on cellular behavior, thereby elucidating its role in various biological pathways and disease contexts.

The primary function of these cell lines lies in their ability to provide a stable model system where the ETS2 gene has been deliberately disrupted using advanced genomic editing technologies such as CRISPR/Cas9. This allows scientists to investigate the downstream effects of ETS2 loss on gene expression profiles, signaling pathways, and phenotypic changes in response to various stimuli. By employing these cell lines, researchers can identify critical interactions and regulatory networks influenced by ETS2, which may lead to insights in oncogenesis, developmental biology, and other areas of cellular research.

In both research and clinical applications, ETS2 Gene Knockout Cell Lines serve as valuable platforms for drug discovery, therapeutic development, and mechanistic studies of diseases such as cancer, where ETS2 is known to be dysregulated. The ability to observe the direct effects of gene knockout in a controlled setting enhances the translational potential of findings, bridging the gap between laboratory research and clinical applications.

What sets these specific cell lines apart from alternatives is their high specificity and reliability. Traditional methods of gene silencing, such as RNA interference, can lead to off-target effects; however, knockout models provide a definitive means of assessing gene function by completely eliminating expression. Additionally, the knockout lines are rigorously validated to ensure effective disruption and maintain cellular integrity, thus allowing for reproducible results.

For researchers and clinicians, the value of ETS2 Gene Knockout Cell Lines lies not only in their precision and reliability but also in the enhanced understanding they offer regarding gene function and its implications for health and disease. This product empowers scientists to delve deeper into the complexities of gene interactions and potentially uncover novel therapeutic targets.

Our company prides itself on its expertise in developing high-quality biological products that meet the evolving needs of researchers. With a commitment to advancing scientific knowledge, we continue to enhance our offerings to support groundbreaking research and innovative solutions in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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