Gene: ESYT3
Official Full Name: extended synaptotagmin 3provided by HGNC
Gene Summary: Predicted to enable calcium ion binding activity and phospholipid binding activity. Predicted to be involved in endoplasmic reticulum-plasma membrane tethering and lipid transport. Located in cytoplasmic side of plasma membrane; endoplasmic reticulum membrane; and endoplasmic reticulum-plasma membrane contact site. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25364 | ESYT3 Knockout cell line (HeLa) | Human | ESYT3 | 1:3~1:6 | Negative | Online Inquiry |
ESYT3 Gene Knockout Cell Lines are sophisticated biological tools engineered for the precise study of the ESYT3 gene, which encodes for a vital protein involved in lipid metabolism and membrane traffic. By effectively disrupting the gene, these cell lines provide researchers with a means to explore the functional roles of ESYT3 in cellular processes such as endocytosis, exocytosis, and the regulation of lipid droplet dynamics.
The key function of ESYT3 Gene Knockout Cell Lines lies in their ability to mimic disease states by eliminating the expression of the ESYT3 protein. This allows for the assessment of cellular pathways impacted by lipid metabolism changes and provides insights into conditions such as obesity, metabolic syndrome, and various lipid-related disorders. The knockout mechanism is characterized by CRISPR-Cas9 technology, ensuring high specificity and minimal off-target effects, allowing scientists to derive reliable data for both basic research and therapeutic development.
The scientific importance of these cell lines cannot be overstated, as they afford a controlled environment in which to dissect the molecular underpinnings of lipid-related pathologies. In clinical settings, understanding the nuances of ESYT3 function can inform potential therapeutic strategies, ultimately aiming to enhance patient outcomes in metabolic diseases.
A key advantage of ESYT3 Gene Knockout Cell Lines is their robust adaptability for various applications, including high-throughput screening, metabolic profiling, and drug discovery. Compared to traditional models, these knockout lines offer unprecedented precision and reproducibility, fostering yield consistency in experimental results.
Researchers, clinicians, and pharmaceutical developers will find substantive value in leveraging ESYT3 Gene Knockout Cell Lines as they advance our understanding of lipid metabolism and pave the way for innovative interventions. Additionally, our commitment to excellence in the biotechnological domain ensures that our products are backed by rigorous quality control and extensive support, making us a trusted partner in scientific inquiry and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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