Gene: EPB41L4B
Official Full Name: erythrocyte membrane protein band 4.1 like 4Bprovided by HGNC
Gene Summary: Predicted to be a structural constituent of cytoskeleton. Involved in several processes, including positive regulation of cell adhesion; positive regulation of keratinocyte migration; and wound healing. Acts upstream of or within actomyosin structure organization. Located in apical part of cell; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21608 | EPB41L4B Knockout cell line (HeLa) | Human | EPB41L4B | 1:3~1:6 | Negative | Online Inquiry |
KO21609 | EPB41L4B Knockout cell line (HCT 116) | Human | EPB41L4B | 1:2~1:4 | Negative | Online Inquiry |
KO21610 | EPB41L4B Knockout cell line (HEK293) | Human | EPB41L4B | 1:3~1:6 | Negative | Online Inquiry |
KO21611 | EPB41L4B Knockout cell line (A549) | Human | EPB41L4B | 1:3~1:4 | Negative | Online Inquiry |
EPB41L4B Gene Knockout Cell Lines represent a sophisticated tool in the realm of genetic research and cellular biology. These engineered cell lines are created by specifically knocking out the EPB41L4B gene, which encodes a membrane-associated protein involved in cytoskeletal organization and cellular integrity. By disabling this gene, researchers can elucidate the gene's role in various biological processes, including cell proliferation, differentiation, and signal transduction pathways.
The cell lines function by utilizing CRISPR/Cas9 technology to introduce precise deletions in the EPB41L4B gene, allowing for the thorough examination of its absence on cellular behavior and interactions. This knockout methodology enables scientists to explore the gene's involvement in disease mechanisms, particularly in cancer and neurological disorders, where alterations in cytoskeletal dynamics are critical. The targeted nature of these knockouts makes it easier to assess phenotype changes and gene-protein interactions, fostering a deeper understanding of the biological implications of the EPB41L4B gene.
From a scientific perspective, these cell lines are invaluable for both research and clinical applications. They provide a reliable model system for drug discovery, toxicity screening, and the investigation of novel therapeutic targets, particularly for conditions linked to cellular dysfunctions. The unique nature of EPB41L4B knockout cell lines allows researchers to obtain specific insights that would be challenging to achieve with traditional methods or alternative non-targeted approaches.
What sets EPB41L4B Gene Knockout Cell Lines apart from other genetic tools is their accessibility and adaptability. They can be easily incorporated into existing research protocols, providing researchers and clinicians with a straightforward model for varied experimental paradigms. Their versatility also supports the exploration of gene functions in tandem with other cellular pathways, making them excellent candidates for multi-disciplinary studies.
By investing in EPB41L4B Gene Knockout Cell Lines, users can capitalize on our extensive expertise in genetic engineering and cellular models. We are committed to providing high-quality biological products that meet the evolving needs of researchers and clinicians dedicated to advancing scientific knowledge and therapeutic applications.
Please note that all services are for research use only. Not intended for any clinical use.
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