Gene: EPB41L1
Official Full Name: erythrocyte membrane protein band 4.1 like 1provided by HGNC
Gene Summary: Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38018 | EPB41L1 Knockout cell line (HeLa) | Human | EPB41L1 | 1:3~1:6 | Negative | Online Inquiry |
KO38019 | EPB41L1 Knockout cell line (HCT 116) | Human | EPB41L1 | 1:2~1:4 | Negative | Online Inquiry |
KO38020 | EPB41L1 Knockout cell line (HEK293) | Human | EPB41L1 | 1:3~1:6 | Negative | Online Inquiry |
KO38021 | EPB41L1 Knockout cell line (A549) | Human | EPB41L1 | 1:3~1:4 | Negative | Online Inquiry |
EPB41L1 Gene Knockout Cell Lines represent a sophisticated tool for researchers investigating the role of the EPB41L1 gene in cellular processes. These genetically modified cell lines are created through the targeted knockout of the EPB41L1 gene, resulting in a model that allows for the study of the gene's function and its implications in various biological contexts. The knockout mechanism encompasses the use of CRISPR-Cas9 technology, which facilitates precise deletions or alterations within the gene, leading to its complete inactivation.
The primary function of the EPB41L1 gene relates to its role in cytoskeletal framework organization and cellular adhesion, making these knockout cell lines particularly valuable for studies on cell migration, proliferation, and signaling pathways. By eliminating EPB41L1, researchers can elucidate its contributions to diseases such as cancer, autoimmune disorders, and other conditions where cell behavior is disrupted.
In research and clinical settings, these cell lines provide a reliable platform for drug discovery and development, facilitating high-throughput screening of therapeutic compounds that target pathways associated with EPB41L1. Furthermore, they serve as essential tools for validating gene function in various genetic backgrounds, allowing for deeper insights into gene networks and their interactions.
Compared to alternative models, such as traditional knockdown techniques, EPB41L1 Gene Knockout Cell Lines offer a more robust and permanent genetic modification. This permanence allows for more consistent results in long-term studies, enabling researchers to draw clearer conclusions about gene function.
For researchers, clinicians, and biotechnology companies focused on genetic research, the availability of EPB41L1 Gene Knockout Cell Lines is invaluable. They create unparalleled opportunities for advancing scientific understanding and developing targeted therapies. Our company specializes in high-quality genetic models and tools tailored for such applications, ensuring that you have access to reliable products that propel your research or clinical initiatives forward.
Please note that all services are for research use only. Not intended for any clinical use.
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