Gene: ENOX1
Official Full Name: ecto-NOX disulfide-thiol exchanger 1provided by HGNC
Gene Summary: The protein encoded by this gene is involved in plasma membrane electron transport pathways. The encoded protein has both a hydroquinone (NADH) oxidase activity and a protein disulfide-thiol interchange activity. The two activities cycle with a periodicity of 24 minutes, with one activity being at its peak when the other is at its lowest. [provided by RefSeq, Dec 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17982 | ENOX1 Knockout cell line (HeLa) | Human | ENOX1 | 1:3~1:6 | Negative | Online Inquiry |
KO17983 | ENOX1 Knockout cell line (HCT 116) | Human | ENOX1 | 1:2~1:4 | Negative | Online Inquiry |
KO17984 | ENOX1 Knockout cell line (HEK293) | Human | ENOX1 | 1:3~1:6 | Negative | Online Inquiry |
ENOX1 Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted disruption of the ENOX1 gene, which encodes a protein involved in the process of oxidative metabolism and cell signaling. By knocking out the ENOX1 gene, these cell lines provide a valuable tool for researchers studying the molecular mechanisms of redox biology, cancer progression, and the cellular response to stress. The specific alteration of this gene allows for the examination of its functions in various cellular contexts, enabling scientists to understand better how ENOX1 contributes to pathology and normal physiological processes.
The primary mechanism through which ENOX1 operates involves its role in generating reactive oxygen species (ROS), which can modulate signaling pathways and influence cellular proliferation and differentiation. By using ENOX1 Gene Knockout Cell Lines, investigators can assess how the absence of ENOX1 alters metabolic activity, impacts oxidative stress responses, and modifies cellular morphology. This knockout approach can illuminate the gene's role in tumorigenesis and disease states, making these cell lines essential for exploratory research into targeted therapies.
The significance of ENOX1 Gene Knockout Cell Lines extends into both research and clinical applications. They are particularly useful in preclinical studies aimed at validating ENOX1 as a therapeutic target for various diseases, including cancers and neurodegenerative disorders. Their utility in drug screening and biomarker discovery further amplifies their relevance in translational research.
Compared to conventional cell lines that may express the ENOX1 gene, our genetically modified knockout cell lines offer a distinct advantage by enabling the precise analysis of ENOX1 function and eliminating confounding variable interactions. Researchers choosing ENOX1 Gene Knockout Cell Lines gain access to a reliable model that can provide clearer insights into the underlying biology of diseases related to oxidative stress and mitochondrial dysfunction.
With our comprehensive expertise in cellular biology and genetic engineering, we leverage advanced technologies to develop high-quality biological products like ENOX1 Gene Knockout Cell Lines. Our commitment to innovation and research support positions us as a leading partner in advancing scientific discovery and enhancing therapeutic strategies.
Please note that all services are for research use only. Not intended for any clinical use.
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