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ENDOD1 Knockout Cell Lines

Gene: ENDOD1

Official Full Name: endonuclease domain containing 1provided by HGNC

Gene Summary: Predicted to enable endonuclease activity; metal ion binding activity; and nucleic acid binding activity. Predicted to be involved in innate immune response. Located in extracellular exosome and membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29945 ENDOD1 Knockout cell line (HeLa) Human ENDOD1 1:3~1:6 Negative Online Inquiry
KO29946 ENDOD1 Knockout cell line (HCT 116) Human ENDOD1 1:2~1:4 Negative Online Inquiry
KO29947 ENDOD1 Knockout cell line (HEK293) Human ENDOD1 1:3~1:6 Negative Online Inquiry
KO29948 ENDOD1 Knockout cell line (A549) Human ENDOD1 1:3~1:4 Negative Online Inquiry

Background

ENDOD1 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology, specifically designed to facilitate the study of endodermal development and its associated pathways. These cell lines have been engineered to lack the ENDOD1 gene, which is critical for various embryonic processes, including the differentiation of pluripotent stem cells into definitive endoderm. By creating a model that mimics gene knockout scenarios, researchers can unravel the complexities of gene function and its implications in development, disease, and regenerative medicine.

The key function of ENDOD1 Gene Knockout Cell Lines lies in their ability to enable precise investigation into the biological roles of the ENDOD1 gene. This gene is known to influence cellular signaling pathways, and its absence allows for detailed analyses of compensatory mechanisms and phenotypic outcomes. Researchers can culture these cell lines under various conditions to further explore how the absence of ENDOD1 affects cellular processes such as proliferation, apoptosis, and differentiation.

Scientifically, these cell lines are invaluable in both research and clinical contexts. In developmental biology studies, the ENDOD1 knockout model can be a vital asset for understanding conditions like congenital malformations and organogenesis. Furthermore, these cell lines can be applied in drug development, as they allow for screening therapeutic interventions that target endodermal processes, enhancing the potential for discovering novel treatments.

Compared to traditional cell lines, the ENDOD1 Gene Knockout Cell Lines offer unique advantages, including the elimination of confounding variables associated with gene expression. This specificity can reduce experimental noise and enhance the reproducibility of results. Additionally, these cell lines represent a more targeted approach than broad-spectrum knockdown techniques, allowing researchers to focus on the precise effects of ENDOD1 absence.

For researchers and clinicians invested in the fields of developmental biology, stem cell research, and regenerative medicine, the ENDOD1 Gene Knockout Cell Lines provide a powerful tool to deepen their understanding of gene function and its role in health and disease. Our company has a strong commitment to delivering innovative, high-quality biological products, backed by extensive expertise in genetic engineering and cell line development. We are dedicated to supporting your research endeavors with reliable, advanced solutions that drive discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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