Gene: EMILIN1
Official Full Name: elastin microfibril interfacer 1provided by HGNC
Gene Summary: This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung. [provided by RefSeq, Sep 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31197 | EMILIN1 Knockout cell line (HEK293) | Human | EMILIN1 | 1:3~1:6 | Negative | Online Inquiry |
EMILIN1 Gene Knockout Cell Lines are genetically engineered cellular models that have had the EMILIN1 gene selectively disrupted, allowing researchers to study the biological roles and implications of this gene in various physiological and pathological contexts. EMILIN1, or elastin microfibril interfacer 1, is known to play a crucial role in the extracellular matrix, influencing tissue elasticity, structural integrity, and cellular signaling pathways.
The primary function of these knockout cell lines is to facilitate the investigation of the EMILIN1 gene's contributions to cellular function, particularly in areas related to development, tissue remodeling, and disease processes such as fibrosis and cancer progression. By observing the phenotypic and functional changes that occur in the absence of the EMILIN1 gene, researchers can elucidate its role in cellular adhesion, migration, and proliferation.
The scientific significance of EMILIN1 Gene Knockout Cell Lines lies in their potential applications in molecular biology, genetic research, and drug development. They can serve as invaluable tools for studying the mechanisms underlying various diseases, aiding the identification of therapeutic targets and the development of novel treatment strategies. Additionally, these cell lines can assist in regenerative medicine studies aimed at tissue repair and engineering.
Compared to alternative models, such as transient or stable knockdown systems, EMILIN1 Gene Knockout Cell Lines offer greater specificity and permanence in gene disruption, leading to more reliable and reproducible results. This stability can enhance the validity of experimental findings and accelerate progress in research endeavors.
For researchers and clinicians, the value of EMILIN1 Gene Knockout Cell Lines is clear. They provide a targeted approach to dissecting the complex biological functions of EMILIN1, ultimately advancing our understanding of its role in health and disease. With our company's deep expertise in genetic engineering and a commitment to delivering high-quality biological products, we provide researchers with the tools they need to drive innovation in their fields.
Please note that all services are for research use only. Not intended for any clinical use.
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