Home / EMC4 Knockout Cell Lines

EMC4 Knockout Cell Lines

Gene: EMC4

Official Full Name: ER membrane protein complex subunit 4provided by HGNC

Gene Summary: Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Located in endoplasmic reticulum membrane. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22821 EMC4 Knockout cell line (HeLa) Human EMC4 1:3~1:6 Negative Online Inquiry
KO22822 EMC4 Knockout cell line (HCT 116) Human EMC4 1:2~1:4 Negative Online Inquiry
KO22823 EMC4 Knockout cell line (HEK293) Human EMC4 1:3~1:6 Negative Online Inquiry
KO22824 EMC4 Knockout cell line (A549) Human EMC4 1:3~1:4 Negative Online Inquiry

Background

EMC4 Gene Knockout Cell Lines represent a significant advancement in the field of cellular biology and genetic research. These specially engineered cell lines have undergone targeted gene disruption of the EMC4 gene, which is pivotal in various cellular processes, including cellular response to stress and protein stability regulation. By completely knocking out the EMC4 gene, researchers can elucidate its role and the biological pathways it influences, thus providing insights into its contributions to human diseases and potential therapeutic targets.

The primary function of the EMC4 Gene Knockout Cell Lines lies in facilitating biochemical and molecular analyses to unravel the gene's biological implications. Utilizing CRISPR-Cas9 gene-editing technology ensures precise and efficient gene disruption, allowing for a clean study of downstream effects without the confounding influences of EMC4 expression. This cutting-edge mechanism not only enhances experimental reproducibility but also accelerates the pace of discovery in research environments.

Scientifically, these knockout cell lines are invaluable in disease modeling, drug discovery, and gene function studies. In clinical settings, they can help identify EMC4-related disorders and assess the impact of pharmacological agents on EMC4's associated pathways. Furthermore, they serve as a robust tool for screening potential compounds that could modulate EMC4 expression, paving the way for novel therapeutic strategies.

Compared to conventional cell lines, the uniqueness of the EMC4 Gene Knockout Cell Lines lies in their specificity and tailor-made design. While traditional cell lines may exhibit residual EMC4 functionality, these targeted knockout lines offer a clean slate for researchers seeking to study the direct effects of EMC4 absence. This enables more accurate and reliable experimental outcomes, saving time and resources in research efforts.

For researchers and clinicians alike, the EMC4 Gene Knockout Cell Lines provide a crucial technology that could significantly enhance the understanding of gene functions in health and disease contexts. The ability to explore EMC4's role rigorously positions these cell lines as an essential resource in the molecular biology toolkit.

With our longstanding expertise in the development of advanced genetic research products, we are committed to providing high-quality, reliable biological tools that facilitate innovative research, ensuring that our clients stay at the forefront of scientific advancements.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.