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ELAVL1 Knockout Cell Lines

Gene: ELAVL1

Official Full Name: ELAV like RNA binding protein 1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07458 ELAVL1 Knockout cell line (HeLa) Human ELAVL1 1:3~1:6 Negative Online Inquiry
KO07459 ELAVL1 Knockout cell line (HCT 116) Human ELAVL1 1:2~1:4 Negative Online Inquiry
KO07460 ELAVL1 Knockout cell line (HEK293) Human ELAVL1 1:3~1:6 Negative Online Inquiry
KO07461 ELAVL1 Knockout cell line (A549) Human ELAVL1 1:3~1:4 Negative Online Inquiry

Background

ELAVL1 Gene Knockout Cell Lines represent a significant advancement in the field of molecular biology, providing a robust tool for researchers investigating gene function and regulatory mechanisms. The ELAVL1 gene encodes a member of the hnRNP family involved in mRNA stability and regulation, crucial for various cellular processes including differentiation, stress response, and neuronal development. By employing CRISPR-Cas9 technology, our cell lines effectively eliminate ELAVL1 expression, allowing for the detailed study of its role in cellular pathways and the phenotypic consequences of its absence.

The key functionality of these knockout cell lines lies in their ability to facilitate experimental designs that elucidate the molecular underpinnings of mRNA metabolism and gene expression regulation. Researchers can employ these lines to assess changes in transcriptomic stability, protein synthesis, and cellular response under stress conditions. Furthermore, the ELAVL1 knockout model serves as a valuable resource for understanding how dysregulation of this protein may contribute to diseases such as cancer and neurodegenerative disorders.

One of the unique selling points of our ELAVL1 Gene Knockout Cell Lines is their high specificity and efficiency, which sets them apart from traditional gene silencing methods such as RNA interference or antisense oligonucleotides. These cell lines provide a permanent knockout of the ELAVL1 gene, offering more consistent and reproducible results over time, which is critical for long-term studies and therapeutic research.

For researchers and clinicians alike, these knockout cell lines are invaluable for dissecting the complexities of gene regulation and exploring novel therapeutic avenues. With growing demand for precise genetic models, our product stands out as an essential addition to any molecular biology laboratory.

Our company prides itself on its commitment to advancing scientific research through innovative biological products and the provision of high-quality cell lines tailored for exceptional research outcomes. We leverage the latest CRISPR technology to ensure that our products meet the needs of the biological research community, facilitating breakthroughs in understanding gene function and disease mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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