Gene: EIPR1
Official Full Name: EARP complex and GARP complex interacting protein 1provided by HGNC
Gene Summary: This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq, Dec 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01731 | EIPR1 Knockout cell line (HeLa) | Human | EIPR1 | 1:3~1:6 | Negative | Online Inquiry |
KO01732 | EIPR1 Knockout cell line (HCT 116) | Human | EIPR1 | 1:2~1:4 | Negative | Online Inquiry |
KO01733 | EIPR1 Knockout cell line (HEK293) | Human | EIPR1 | 1:3~1:6 | Negative | Online Inquiry |
KO01734 | EIPR1 Knockout cell line (A549) | Human | EIPR1 | 1:3~1:4 | Negative | Online Inquiry |
EIPR1 Gene Knockout Cell Lines represent a groundbreaking tool for the study of gene function and gene therapy applications. These cell lines are genetically modified to lack the function of the EIPR1 gene, which encodes a protein implicated in various cellular processes including signal transduction and cellular homeostasis. By utilizing CRISPR-Cas9 technology, researchers have successfully rendered these cells devoid of EIPR1 expression, facilitating a broad range of functional assays to elucidate the role of this gene in biological pathways.
The key function of EIPR1 Gene Knockout Cell Lines lies in their ability to serve as an experimental model for understanding the biological consequences of EIPR1 deficiency. These knockouts can be used to investigate cellular phenotype alterations in response to environmental stimuli, drug treatments, and pathological conditions, thus providing insights into mechanisms associated with diseases where EIPR1 is implicated, such as certain cancers and metabolic disorders.
In research and clinical settings, these cell lines are invaluable for drug discovery and development, offering a platform for screening potential therapeutic agents targeting EIPR1-related pathways. The ability to discern the functional outcomes associated with EIPR1 knockout also enhances the understanding of gene interactions, allowing for the identification of compensatory mechanisms and therapeutic strategies to mitigate the effects of EIPR1 loss.
One primary advantage of the EIPR1 Gene Knockout Cell Lines is their specificity and reliability compared to traditional gene silencing methods, such as RNA interference, which can have off-target effects. Additionally, these cell lines are easily integrated into existing laboratory workflows and can be cultured under standard conditions, making them highly accessible for researchers.
For scientists and clinicians focused on gene therapy and mechanistic studies, the EIPR1 Gene Knockout Cell Lines provide powerful, precise tools that are essential for advancing our understanding of genetics and improving therapeutic approaches. Our company specializes in the development of high-quality, genetically engineered cell lines, ensuring that we offer cutting-edge products tailored to the evolving needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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