Gene: EIF2S3B
Official Full Name: eukaryotic translation initiation factor 2 subunit gamma Bprovided by HGNC
Gene Summary: Predicted to enable translation initiation factor activity. Predicted to contribute to tRNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be part of eukaryotic translation initiation factor 2 complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO21109 | EIF2S3B Knockout cell line (HeLa) | Human | EIF2S3B | 1:3~1:6 | Negative | Online Inquiry |
KO21110 | EIF2S3B Knockout cell line (HCT 116) | Human | EIF2S3B | 1:2~1:4 | Negative | Online Inquiry |
KO21111 | EIF2S3B Knockout cell line (HEK293) | Human | EIF2S3B | 1:3~1:6 | Negative | Online Inquiry |
KO21112 | EIF2S3B Knockout cell line (A549) | Human | EIF2S3B | 1:3~1:4 | Negative | Online Inquiry |
EIF2S3B Gene Knockout Cell Lines are specifically engineered cellular models characterized by the targeted deletion of the EIF2S3B gene, which encodes a critical component of the eukaryotic translation initiation factor 2 subunit beta (eIF2β). This gene plays an essential role in the initiation of protein synthesis by facilitating the binding of methionyl-tRNA to the ribosome, influencing cellular response to stress and overall protein homeostasis.
The key function of EIF2S3B Gene Knockout Cell Lines is to provide researchers with a powerful tool to study the implications of disrupted eIF2β function. By observing the phenotypic and molecular changes that occur in these knockout models, scientists can investigate the mechanistic pathways underlying various cellular stress responses, cancer biology, and genetic disorders related to protein synthesis. The absence of EIF2S3B allows for the elucidation of compensatory mechanisms and alternative pathways activated in translation initiation processes, ultimately advancing our understanding of cellular biology.
The scientific importance of these knockout cell lines extends to both research and clinical settings, where they serve as a model to evaluate potential therapeutic interventions aimed at diseases associated with protein synthesis dysregulation. Researchers can utilize these models to screen for drug candidates or to study the effects of specific genetic mutations on cell signaling pathways.
Compared to traditional wild-type cell lines, EIF2S3B Gene Knockout Cell Lines offer unique advantages, including the ability to systematically explore the specific contributions of the eIF2β subunit in various biological contexts. They empower researchers with the capacity to achieve clearer insights into the pathophysiology of diseases and facilitate the development of targeted therapies.
For researchers, clinicians, and pharmaceutical developers, the intrinsic value of EIF2S3B Gene Knockout Cell Lines lies in their precision and relevance to contemporary biomedical questions. By providing deeper insights into the roles of translation initiation factors in health and disease, these knockout cell lines enhance the ability to bridge the gap between basic science and clinical application.
Our company prides itself on its commitment to advancing biological research through high-quality, innovative products. With a deep understanding of genetic engineering techniques and a robust portfolio of advanced cell lines, we are dedicated to supporting the scientific community’s quest for knowledge and breakthroughs in health-related research.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.