Gene: EIF2AK1
Official Full Name: eukaryotic translation initiation factor 2 alpha kinase 1provided by HGNC
Gene Summary: The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27837 | EIF2AK1 Knockout cell line (HeLa) | Human | EIF2AK1 | 1:3~1:6 | Negative | Online Inquiry |
KO27838 | EIF2AK1 Knockout cell line (HCT 116) | Human | EIF2AK1 | 1:2~1:4 | Negative | Online Inquiry |
KO27839 | EIF2AK1 Knockout cell line (HEK293) | Human | EIF2AK1 | 1:3~1:6 | Negative | Online Inquiry |
KO27840 | EIF2AK1 Knockout cell line (A549) | Human | EIF2AK1 | 1:3~1:4 | Negative | Online Inquiry |
EIF2AK1 Gene Knockout Cell Lines are genetically modified cell lines designed to specifically disrupt the EIF2AK1 gene, which encodes the eIF2α kinase involved in cellular stress responses. The primary function of these knockout cell lines is to investigate the mechanistic roles of eIF2AK1 in regulating protein synthesis and the stress response pathways. By generating a loss-of-function mutation in the EIF2AK1 gene, researchers can elucidate how alterations in this pathway affect cell growth, survival, and response to stressors, such as hypoxia or nutrient deprivation.
The scientific importance of EIF2AK1 Gene Knockout Cell Lines spans various research disciplines, including cancer biology, neurobiology, and immunology. These cell lines serve as an invaluable tool to study the role of eIF2AK1 in translational control during pathological conditions, providing insights into novel therapeutic targets. In clinical settings, understanding eIF2AK1 functions may lead to the development of innovative therapies for diseases associated with dysregulated stress responses, including neurodegenerative disorders and cancers.
Compared to traditional methods, such as RNA interference or chemical inhibitors, the use of knockout technology provides a more permanent solution to gene disruption, ensuring robust and reproducible results. Furthermore, our EIF2AK1 Gene Knockout Cell Lines are characterized by high specificity and minimal off-target effects, allowing for precise interpretations of experimental outcomes.
This product offers exceptional value to researchers and clinicians aiming to deepen their understanding of cellular response mechanisms and stress adaptation. With these knockout cell lines, users can accelerate discovery and innovation in their studies, leading to potential advancements in treatment modalities.
Our company is dedicated to providing high-quality biological products supported by rigorous scientific research and expertise, ensuring that our customers have access to tools that meet the demands of cutting-edge laboratory work.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.