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EIF1AY Knockout Cell Lines

Gene: EIF1AY

Official Full Name: eukaryotic translation initiation factor 1A Y-linkedprovided by HGNC

Gene Summary: This gene is located on the non-recombining region of the Y chromosome. It encodes a protein related to eukaryotic translation initiation factor 1A (EIF1A), which may function in stabilizing the binding of the initiator Met-tRNA to 40S ribosomal subunits. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33597 EIF1AY Knockout cell line (HCT 116) Human EIF1AY 1:2~1:4 Negative Online Inquiry
KO33598 EIF1AY Knockout cell line (A549) Human EIF1AY 1:3~1:4 Negative Online Inquiry

Background

EIF1AY Gene Knockout Cell Lines represent a significant advancement in the study of gene function and regulation, particularly within the context of male fertility and cancer research. These engineered cell lines have undergone precise genetic modification to effectively inactivate the EIF1AY gene, which encodes a protein component of the translation initiation complex, playing critical roles in the modulation of protein synthesis.

The primary function of these knockout lines is to serve as a model for elucidating the cellular processes influenced by the EIF1AY gene. The absence of this gene allows researchers to investigate the downstream effects on cellular development, proliferation, and differentiation, providing insights into the biological pathways affected by its loss. This is particularly valuable in studies related to spermatogenesis, where EIF1AY has been implicated in the translation of specific mRNAs necessary for sperm development.

Scientifically, these knockout cell lines find applications in both basic and applied research, enabling investigations into pathologies associated with aberrant gene regulation. In clinical settings, they provide a platform for assessing drug responses and therapeutic strategies aimed at restoring normal function in diseases where EIF1AY dysregulation is observed.

The distinct advantage of using EIF1AY Gene Knockout Cell Lines lies in their specificity and reliability over traditional models, which may not completely recapitulate the gene's role. Compared to other available models, these cell lines facilitate more detailed and controlled experiments, thereby enhancing the robustness of research findings.

For researchers and clinicians dedicated to understanding complex biological systems, these knockout cell lines are invaluable tools that drive forward our knowledge, aiding the development of innovative interventions. Our company prides itself on delivering high-quality biological products backed by extensive expertise and a commitment to supporting scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

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