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EFR3B Knockout Cell Lines

Gene: EFR3B

Official Full Name: EFR3 homolog Bprovided by HGNC

Gene Summary: Involved in phosphatidylinositol phosphate biosynthetic process and protein localization to plasma membrane. Located in actin cytoskeleton; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30074 EFR3B Knockout cell line (HEK293) Human EFR3B 1:3~1:6 Negative Online Inquiry
KO30075 EFR3B Knockout cell line (A549) Human EFR3B 1:3~1:4 Negative Online Inquiry

Background

EFR3B Gene Knockout Cell Lines are specialized cellular models generated to investigate the functions of the EFR3B gene, a critical regulator involved in various signaling pathways and cellular processes. These cell lines are created using advanced CRISPR/Cas9 genomic editing techniques, ensuring a precise knockout of the EFR3B gene, which enables researchers to study the resultant phenotypic changes and biological implications of EFR3B loss of function.

The EFR3B gene encodes a protein involved in phosphoinositide metabolism, which plays a pivotal role in the regulation of cellular signaling pathways associated with growth, differentiation, and stress responses. By employing EFR3B knockout cell lines, scientists can elucidate the gene's contributions to cellular homeostasis and its potential implications in disease states such as cancer and metabolic disorders. These models facilitate high-throughput screening and functional assays that can accelerate the discovery of novel therapeutic targets.

The scientific importance of EFR3B Gene Knockout Cell Lines extends to both fundamental research and clinical applications. They serve as valuable tools for drug development, enabling researchers to test the effects of potential therapeutics in a controlled environment without the confounding effects of an intact EFR3B gene. Moreover, these cell lines have a unique advantage over conventional models; they provide a more precise representation of genetic alterations found in human pathologies, which enhances translational research efforts.

Researchers and clinicians can significantly benefit from the robustness and specificity of EFR3B knockout cell lines, as they yield reproducible results that contribute to a deeper understanding of the EFR3B gene's role in health and disease. The availability of these engineered cell lines allows for innovative experimental designs that can lead to breakthroughs in therapies for diseases linked to EFR3B dysfunction.

As a leader in the field of gene editing technologies, our company is dedicated to providing high-quality, validated biological products, ensuring that researchers have access to the best tools necessary for their groundbreaking work. Our expertise in genomic engineering translates into reliable models that can support your research objectives effectively and efficiently.

Please note that all services are for research use only. Not intended for any clinical use.

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