Gene: EFCAB10
Official Full Name: EF-hand calcium binding domain 10provided by HGNC
Gene Summary: Predicted to enable calcium ion binding activity. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18057 | EFCAB10 Knockout cell line (HeLa) | Human | EFCAB10 | 1:3~1:6 | Negative | Online Inquiry |
KO18058 | EFCAB10 Knockout cell line (HCT 116) | Human | EFCAB10 | 1:2~1:4 | Negative | Online Inquiry |
KO18059 | EFCAB10 Knockout cell line (HEK293) | Human | EFCAB10 | 1:3~1:6 | Negative | Online Inquiry |
KO18060 | EFCAB10 Knockout cell line (A549) | Human | EFCAB10 | 1:3~1:4 | Negative | Online Inquiry |
EFCAB10 Gene Knockout Cell Lines are meticulously engineered cellular models designed to study the EFCAB10 gene's role in various biological processes. EFCAB10 (EF-hand calcium-binding protein 10) plays a significant role in calcium signaling, influencing numerous cellular functions, including cell proliferation, differentiation, and apoptosis. The knockout of this gene allows researchers to observe the resultant phenotypic changes, yielding insights into the mechanisms by which EFCAB10 impacts cellular behavior.
These cell lines work through a targeted gene disruption strategy, where CRISPR/Cas9 technology is utilized to create precise deletions within the EFCAB10 gene. This process effectively inhibits the gene's expression, thereby providing researchers with a clean model to investigate its biological functions and contributions to disease states, particularly in cancer research and neurobiology. By utilizing these models, scientists can establish correlations between EFCAB10 deficiency and alterations in signaling pathways, potentially uncovering new therapeutic targets.
The scientific importance of EFCAB10 Gene Knockout Cell Lines extends to their applications in drug development and genetic research. Investigating the pathways influenced by the EFCAB10 gene provides a foundation for understanding diseases such as breast cancer and neurodegenerative disorders, leading to the identification of novel pharmacological agents.
Compared to alternative cellular models, the EFCAB10 gene knockout lines offer unmatched specificity and reliability. The precision of CRISPR technology minimizes off-target effects, thereby ensuring that observed phenotypic changes can be confidently attributed to the EFCAB10 knockout.
For researchers and clinicians focused on advancing their understanding of calcium signaling and its implications in health and disease, these cell lines represent an invaluable resource. Their use can accelerate the discovery of potential therapies and inform clinical strategies.
Our company has a rich background in developing innovative biological products, and we are committed to providing high-quality, reliable tools that empower scientists in their pursuit of knowledge and breakthroughs in biomedicine.
Please note that all services are for research use only. Not intended for any clinical use.
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