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ECHDC1 Knockout Cell Lines

Gene: ECHDC1

Official Full Name: ethylmalonyl-CoA decarboxylase 1provided by HGNC

Gene Summary: Predicted to enable carboxy-lyase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to be located in cytoplasm and membrane. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20783 ECHDC1 Knockout cell line (HeLa) Human ECHDC1 1:3~1:6 Negative Online Inquiry
KO20784 ECHDC1 Knockout cell line (HCT 116) Human ECHDC1 1:2~1:4 Negative Online Inquiry
KO20785 ECHDC1 Knockout cell line (HEK293) Human ECHDC1 1:3~1:6 Negative Online Inquiry
KO20786 ECHDC1 Knockout cell line (A549) Human ECHDC1 1:3~1:4 Negative Online Inquiry

Background

ECHDC1 Gene Knockout Cell Lines are a specialized biotechnology tool designed to facilitate the study of the ECHDC1 gene, which encodes enoyl-CoA hydratase domain-containing protein 1, a critical enzyme involved in lipid metabolism and mitochondrial function. By creating a knockout model, researchers can explore the functional role of ECHDC1 and its implications in various biological processes.

These cell lines operate by utilizing CRISPR-Cas9 technology to induce targeted deletions within the ECHDC1 gene, effectively disrupting its expression. This innovative mechanism allows scientists to observe the resulting phenotypic changes, providing insights into the gene's contribution to metabolic disorders and cellular respiration. By eliminating functional ECHDC1, researchers can examine how this impacts fatty acid metabolism, energy production, and the cellular response to oxidative stress, opening avenues for understanding diseases linked to mitochondrial dysfunction.

The scientific importance of ECHDC1 Gene Knockout Cell Lines is underscored by their versatility in both research and clinical applications. They hold potential for modeling diseases such as obesity, type 2 diabetes, and certain neurodegenerative conditions, making them valuable resources in drug discovery and development. Additionally, these cell lines are instrumental in defining the biological pathways regulated by ECHDC1, which may lead to novel therapeutic targets.

Compared to conventional cell lines, ECHDC1 Gene Knockout Cell Lines offer significant advantages, including precise gene editing and the ability to generate highly reproducible results. Their use reduces experimental variability and enhances the validity of findings, thereby increasing overall research efficiency.

For researchers, clinicians, and pharmaceutical companies seeking to advance their understanding of metabolic pathways or develop targeted therapies, ECHDC1 Gene Knockout Cell Lines provide a unique resource that bridges basic research and clinical application. Our company prides itself on delivering high-quality biological products backed by rigorous scientific research and expertise, ensuring that you have access to reliable tools for your investigative needs.

Please note that all services are for research use only. Not intended for any clinical use.

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