Gene: EAF2
Official Full Name: ELL associated factor 2provided by HGNC
Gene Summary: Enables transcription elongation factor activity. Involved in positive regulation of transcription by RNA polymerase II and regulation of transcription elongation by RNA polymerase II. Part of transcription elongation factor complex. Biomarker of prostate cancer. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18093 | EAF2 Knockout cell line (HeLa) | Human | EAF2 | 1:3~1:6 | Negative | Online Inquiry |
KO18094 | EAF2 Knockout cell line (HCT 116) | Human | EAF2 | 1:2~1:4 | Negative | Online Inquiry |
KO18095 | EAF2 Knockout cell line (HEK293) | Human | EAF2 | 1:3~1:6 | Negative | Online Inquiry |
KO18096 | EAF2 Knockout cell line (A549) | Human | EAF2 | 1:3~1:4 | Negative | Online Inquiry |
EAF2 Gene Knockout Cell Lines represent a pivotal tool in molecular biology, designed to provide researchers with a powerful model for studying gene function and its implications in various biological pathways. The EAF2 gene, known for its role in RNA processing and tumor suppression, has been targeted in these cell lines to elucidate its contributions to cellular processes. By knocking out EAF2, researchers can observe the resultant phenotypic changes and understand the gene's involvement in cellular growth, apoptosis, and gene regulation.
The mechanism of action relies on CRISPR/Cas9 gene editing technology, which allows for precise disruption of the EAF2 gene. This technique not only ensures high efficiency of gene knockout but also minimizes off-target effects, fostering reliable experimental outcomes. These cell lines serve as an essential platform for investigating the role of EAF2 in cancer biology, including its potential interactions with oncogenic pathways and the relevance in therapeutic resistance.
In the realm of scientific research and clinical applications, EAF2 Gene Knockout Cell Lines possess significant importance. They can facilitate the discovery of novel targets for drug development, inform the mechanistic understanding of diseases linked to EAF2 dysfunction, and aid in the identification of biomarkers for patient stratification. Compared to alternative models, such as transient knockdown systems, these stable knockout lines provide an invaluable resource for long-term studies and reproducibility of results.
For researchers and clinicians, leveraging EAF2 Gene Knockout Cell Lines unlocks the potential to contribute substantially to the field of genetics and therapeutic innovation. Their value lies in enabling detailed functional analyses, supporting drug efficacy studies, and enhancing our understanding of the complex biology surrounding EAF2.
With a proven track record in gene editing technologies and a commitment to advancing biological research, our company offers a suite of high-quality products, including EAF2 Gene Knockout Cell Lines, engineered to empower the scientific community and accelerate discoveries in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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