Gene: Dancr
Official Full Name: differentiation antagonizing non-protein coding RNAprovided by MGI
Gene Summary: Acts upstream of or within response to wounding. Is expressed in several structures, including heart; intestine; limb skin; liver; and lung. Orthologous to human DANCR (differentiation antagonizing non-protein coding RNA). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01232 | Dancr Knockout cell line(RAW 264.7) | Mouse | Dancr | 1:2-1:3 | Negative | Online Inquiry |
Dancr Gene Knockout Cell Lines are precision-engineered cellular models designed to facilitate the study of the long non-coding RNA (lncRNA) known as Dancr (Differentiation Antisense Non-coding RNA). These cell lines are develop using CRISPR-Cas9 technology to effectively delete the Dancr gene, providing a valuable tool for scientists investigating the regulatory roles of lncRNAs in gene expression, cellular differentiation, and various biological processes.
The primary function of Dancr Gene Knockout Cell Lines lies in their ability to allow researchers to elucidate the specific biological pathways and molecular mechanisms impacted by the absence of Dancr. By comparing the knockout lines with their wild-type counterparts, scientists can measure changes in transcriptional profiles, epigenetic modifications, and cellular behaviors that highlight Dancr's contributions to cellular dynamics, development, and disease mechanisms, notably in cancer biology and tissue regeneration.
The scientific significance of these knockout cell lines is underscored by their utility in diverse research fields, including developmental biology, oncology, and regenerative medicine. In clinical settings, understanding the function of Dancr can lead to novel therapeutic strategies targeting lncRNA-mediated regulation, potentially leading to breakthroughs in precision medicine.
One of the key advantages of Dancr Gene Knockout Cell Lines is their unparalleled specificity and reliability, resulting from the precise genome editing techniques employed in their creation. This precision allows for reproducible and consistent experimental outcomes, distinguishing these cell lines from traditional methods that may generate off-target effects or variability. Furthermore, their adaptable nature means they can be used alongside a variety of experimental setups, including drug response assays and gene expression analysis.
By adopting Dancr Gene Knockout Cell Lines, researchers and clinicians gain access to a state-of-the-art resource that not only streamlines their investigations but also enhances the reproducibility of their findings. This ultimately positions users at the forefront of cutting-edge research and therapeutic developments.
Our company is committed to delivering advanced biological tools that empower the scientific community. Leveraging years of expertise in molecular biology and cell line development, we provide high-quality products backed by comprehensive customer support, ensuring that our users can accelerate their research endeavors with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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