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DPYSL3 Knockout Cell Lines

Gene: DPYSL3

Official Full Name: dihydropyrimidinase like 3provided by HGNC

Gene Summary: Enables filamin binding activity. Predicted to be involved in several processes, including actin filament organization; regulation of plasma membrane bounded cell projection organization; and response to axon injury. Predicted to act upstream of or within nervous system development. Predicted to be located in several cellular components, including exocytic vesicle; growth cone; and lamellipodium. Predicted to be part of filamentous actin. Predicted to be active in cytosol and synapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38179 DPYSL3 Knockout cell line (HeLa) Human DPYSL3 1:3~1:6 Negative Online Inquiry
KO38180 DPYSL3 Knockout cell line (HCT 116) Human DPYSL3 1:2~1:4 Negative Online Inquiry
KO38181 DPYSL3 Knockout cell line (HEK293) Human DPYSL3 1:3~1:6 Negative Online Inquiry
KO38182 DPYSL3 Knockout cell line (A549) Human DPYSL3 1:3~1:4 Negative Online Inquiry

Background

DPYSL3 Gene Knockout Cell Lines are genetically modified cell lines that have had the DPYSL3 gene, which encodes the dihydropyrimidinase-like 3 protein, selectively disrupted. This allows for the investigation of the functional role of DPYSL3 in cellular processes. The key function of these cell lines lies in their ability to facilitate the study of neuronal development, neuroplasticity, and disease modeling, particularly in the context of neurodegenerative diseases and neurological disorders. Mechanistically, DPYSL3 is involved in the regulation of microtubule dynamics and cell signaling pathways, making its knockout a crucial tool for elucidating its influence on neuronal morphology and function.

The scientific significance of DPYSL3 Gene Knockout Cell Lines extends to various research domains, including neurobiology, pharmacology, and developmental biology. These cell lines serve as invaluable platforms for drug discovery and development, allowing researchers to screen potential therapeutic agents targeting DPYSL3-related pathways. In clinical settings, understanding the role of DPYSL3 may provide insights into the mechanisms underpinning diseases such as Alzheimer's or multiple sclerosis, ultimately advancing therapeutic strategies.

Compared to other gene knockout models, DPYSL3 Gene Knockout Cell Lines offer a unique advantage in providing targeted insights into specific pathways affected by DPYSL3. The precision and reproducibility of our gene editing techniques ensure consistent performance, enhancing the reliability of experimental results. Furthermore, these cell lines are ready-to-use and validated for various assays, saving time and resources for researchers.

By investing in DPYSL3 Gene Knockout Cell Lines, researchers and clinicians gain a powerful asset for their investigations into neuronal function and associated pathologies. Our company, specializing in cutting-edge biological products and gene editing technologies, is committed to supporting scientific advancement with high-quality, validated tools that cater to the needs of the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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