Gene: DPF2
Official Full Name: double PHD fingers 2provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35654 | DPF2 Knockout cell line (HeLa) | Human | DPF2 | 1:3~1:6 | Negative | Online Inquiry |
KO35655 | DPF2 Knockout cell line (HCT 116) | Human | DPF2 | 1:2~1:4 | Negative | Online Inquiry |
KO35656 | DPF2 Knockout cell line (HEK293) | Human | DPF2 | 1:3~1:6 | Negative | Online Inquiry |
KO35657 | DPF2 Knockout cell line (A549) | Human | DPF2 | 1:3~1:4 | Negative | Online Inquiry |
DPF2 gene knockout cell lines are custom-engineered cellular models designed to study the functional role of the DPF2 gene, a key component involved in various biological processes such as chromatin remodeling and transcriptional regulation. These cell lines have been generated using advanced CRISPR/Cas9 technology, resulting in the complete disruption of DPF2 gene expression. As a result, researchers can investigate the downstream effects of DPF2 loss and its contributions to cellular phenotypes, signaling pathways, and disease mechanisms.
The primary function of DPF2 knockout cell lines is to facilitate the examination of the DPF2 gene in cellular contexts such as differentiation, proliferation, and stress responses. By observing the phenotypic alterations and molecular changes in these knockout models, scientists can elucidate the gene's biological significance and potential as a therapeutic target. This makes DPF2 knockout cell lines invaluable tools in both basic and applied research, including drug discovery and translational studies.
In terms of scientific importance, these cell lines serve crucial applications in cancer research, neuroscience, and developmental biology. Investigators can leverage these models to explore the role of DPF2 in oncogenesis, neurological disorders, or even normal developmental processes, ensuring that their studies are grounded in a robust genetic framework.
When compared to alternative approaches such as RNA interference or wild-type cell lines, the DPF2 knockout model provides greater specificity and consistency in gene disruption, minimizing off-target effects and enabling clearer interpretation of experimental results. Additionally, these cell lines are suitable for high-throughput screening and can be adapted for various assays, enhancing their versatility and usability in different research scenarios.
Choosing DPF2 gene knockout cell lines means equipping your laboratory with a precise, state-of-the-art tool essential for advancing understanding of gene function. These cell lines not only elevate experimental rigor but also clarify the complexities of gene regulation. Our company specializes in providing high-quality, custom cell line development, backed by extensive expertise in genetic engineering and cellular biology. Trust our leading-edge products to propel your research forward.
Please note that all services are for research use only. Not intended for any clinical use.
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