Gene: DPCD
Official Full Name: deleted in primary ciliary dyskinesia homolog (mouse)provided by HGNC
Gene Summary: This gene in mouse encodes a protein that may be involved in the generation and maintenance of ciliated cells. In mouse, expression of this gene increases during ciliated cell differentiation, and disruption of this gene has been linked to primary ciliary dyskinesia. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28635 | DPCD Knockout cell line (HeLa) | Human | DPCD | 1:3~1:6 | Negative | Online Inquiry |
KO28636 | DPCD Knockout cell line (HCT 116) | Human | DPCD | 1:2~1:4 | Negative | Online Inquiry |
KO28637 | DPCD Knockout cell line (HEK293) | Human | DPCD | 1:3~1:6 | Negative | Online Inquiry |
KO28638 | DPCD Knockout cell line (A549) | Human | DPCD | 1:3~1:4 | Negative | Online Inquiry |
DPCD Gene Knockout Cell Lines are engineered cellular models designed to facilitate in-depth investigation into the functions of the DPCD gene, which encodes a protein involved in various cellular processes, including DNA damage response and regulation of cell cycle progression. These knockout cell lines are generated using advanced gene-editing techniques such as CRISPR-Cas9, facilitating the targeted disruption of the DPCD gene, resulting in a complete loss of gene function.
The primary mechanism behind these cell lines is the precise excision of specific segments of the DPCD gene, which allows researchers to assess the phenotypic and molecular consequences of DPCD ablation. By utilizing these cell lines, scientists can explore the implications of DPCD loss in cellular pathways that may be relevant in oncology and genetic disorders, thus contributing to a greater understanding of DPCD's role in disease mechanisms.
The scientific significance of DPCD Gene Knockout Cell Lines extends to both research and clinical settings, where they serve as invaluable tools for studying gene function, drug response, and potential therapeutic targets. Their use can accelerate the discovery of biomarkers for disease and provide insights into novel treatment strategies, ultimately enhancing personalized medicine approaches.
Compared to traditional models, such as wild-type or knockdown systems, the DPCD Gene Knockout Cell Lines offer distinct advantages by providing a complete loss-of-function model, which yields clearer interpretations regarding gene function. Additionally, these cell lines exhibit high reproducibility and genetic stability, making them ideal for rigorous experimental setups.
For researchers and clinicians seeking to elucidate the biological ramifications of DPCD disruption, these cell lines are invaluable. They enable precise experimental designs while providing robust data that could lead to breakthroughs in understanding the underlying mechanisms of diseases.
As a company committed to advancing genetic research, our expertise in creating high-quality gene knockout models ensures that scientists have access to cutting-edge tools that empower their studies and foster innovations in biomedicine.
Please note that all services are for research use only. Not intended for any clinical use.
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