Gene: DNAJC30
Official Full Name: DnaJ heat shock protein family (Hsp40) member C30provided by HGNC
Gene Summary: This intronless gene encodes a member of the DNAJ molecular chaperone homology domain-containing protein family. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24994 | DNAJC30 Knockout cell line (HeLa) | Human | DNAJC30 | 1:3~1:6 | Negative | Online Inquiry |
KO24995 | DNAJC30 Knockout cell line (HCT 116) | Human | DNAJC30 | 1:2~1:4 | Negative | Online Inquiry |
KO24996 | DNAJC30 Knockout cell line (HEK293) | Human | DNAJC30 | 1:3~1:6 | Negative | Online Inquiry |
KO24997 | DNAJC30 Knockout cell line (A549) | Human | DNAJC30 | 1:3~1:4 | Negative | Online Inquiry |
DNAJC30 Gene Knockout Cell Lines are specially developed cellular models that have undergone targeted gene disruption of the DNAJC30 gene, a member of the DnaJ/Hsp40 family of proteins. These engineered cell lines are designed to facilitate research investigating the functional role of DNAJC30 in cellular processes, particularly those related to protein folding, trafficking, and stress response. By knocking out the DNAJC30 gene, researchers can explore the protein's specific contributions to various biological pathways, as well as its implications in disease models such as neurodegenerative disorders and cancer.
The key function of these cell lines lies in their ability to provide a controlled environment to study the consequences of DNAJC30 deficiency, enabling the elucidation of the protein's mechanisms in cellular homeostasis. The knockout model allows for the observation of altered protein dynamics, stress responses, and cellular resilience, which are critical for understanding how disruptions in these pathways might lead to pathological states.
From a scientific standpoint, the DNAJC30 Gene Knockout Cell Lines offer essential applications in both basic research and preclinical studies. In the research arena, these cell lines serve as valuable tools for investigating protein interactions and regulatory networks, enabling researchers to dissect the molecular underpinnings of various diseases. Clinically, understanding the role of DNAJC30 could contribute to novel therapeutic strategies for conditions where protein misfolding and aggregation play a significant role.
One of the principal advantages of these cell lines is their specificity; unlike other genetic manipulation methods such as CRISPR or RNA interference, the knockout lines provide a complete gene absence, allowing researchers to capture unequivocal effects of DNAJC30 loss. Moreover, they can be easily maintained and integrated into various experimental setups, offering flexible utility in diverse research contexts.
By choosing the DNAJC30 Gene Knockout Cell Lines, researchers and clinicians benefit from a high-quality, reliable product that enhances their ability to intuitively study the complexities of cellular biology and pathology. The results from experiments using these cell lines are not only pivotal for advancing scientific understanding but also hold the potential to influence future therapeutic developments.
Our company is dedicated to providing cutting-edge biological research tools, bolstered by a strong foundation in molecular biology and genetic engineering. We continually strive to enhance research capabilities, supporting scientists in their quest for innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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