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DMRTA1 Knockout Cell Lines

Gene: DMRTA1

Official Full Name: DMRT like family A1provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to act upstream of or within male mating behavior and ovarian follicle development. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18268 DMRTA1 Knockout cell line (HeLa) Human DMRTA1 1:3~1:6 Negative Online Inquiry
KO18269 DMRTA1 Knockout cell line (A549) Human DMRTA1 1:3~1:4 Negative Online Inquiry

Background

DMRTA1 Gene Knockout Cell Lines are a specialized resource for researchers focusing on the functional analysis of the DMRTA1 gene, which is known to play a significant role in cellular processes such as differentiation and proliferation. The creation of these knockout cell lines utilizes CRISPR-Cas9 gene editing technology to achieve precise inactivation of the DMRTA1 gene, allowing for the examination of its biological functions and implications in various disease models.

The key function of these cell lines hinges on the disruption of DMRTA1 expression, which enables researchers to study the downstream effects on cellular behavior in a controlled environment. By utilizing these knockout models, scientists can gain insight into the gene's role in critical processes such as stem cell maintenance, neurogenesis, and potential oncogenic pathways. This detailed analysis is invaluable for elucidating the mechanisms underlying diseases linked to DMRTA1 dysregulation, thereby advancing our understanding of disease pathology and potential therapeutic targets.

In terms of scientific importance, the DMRTA1 Gene Knockout Cell Lines serve as a powerful tool for both basic research and applied sciences, including drug discovery and the development of gene therapies. By offering a reliable system to investigate gene function, these cell lines can help identify novel biomarkers and therapeutic avenues, which are essential for the progression of clinical research.

What sets DMRTA1 Gene Knockout Cell Lines apart from other models is their high fidelity and reproducibility, resulting from advanced gene editing methodologies. This ensures that researchers can obtain consistent and reliable data, which is crucial for publication and subsequent studies. Furthermore, these cell lines are validated for performance, ensuring that users have a dependable resource for their experimental needs.

Ultimately, the DMRTA1 Gene Knockout Cell Lines are an invaluable asset for researchers, clinicians, and pharmaceutical companies focused on understanding gene function and developing innovative therapies. By partnering with our company, which has a longstanding commitment to providing high-quality biological products and expertise in gene editing technologies, users can be assured that they are equipped with cutting-edge resources to facilitate their research.

Please note that all services are for research use only. Not intended for any clinical use.

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