Gene: DLGAP5
Official Full Name: DLG associated protein 5provided by HGNC
Gene Summary: Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including centrosome localization; kinetochore assembly; and mitotic spindle organization. Located in cytosol; nucleus; and spindle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09268 | DLGAP5 Knockout cell line (HeLa) | Human | DLGAP5 | 1:3~1:6 | Negative | Online Inquiry |
KO09269 | DLGAP5 Knockout cell line (HCT 116) | Human | DLGAP5 | 1:2~1:4 | Negative | Online Inquiry |
KO09270 | DLGAP5 Knockout cell line (HEK293) | Human | DLGAP5 | 1:3~1:6 | Negative | Online Inquiry |
KO09271 | DLGAP5 Knockout cell line (A549) | Human | DLGAP5 | 1:3~1:4 | Negative | Online Inquiry |
DLGAP5 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to disable the DLGAP5 (Disks Large-Associated Protein 5) gene, a critical component in the regulation of cellular signaling pathways and cell division. By employing advanced CRISPR-Cas9 technology, these cell lines facilitate precise gene editing, allowing researchers to study the role of DLGAP5 in various biological processes, including tumorigenesis, mitotic spindle function, and synaptic organization.
The primary function of DLGAP5 is its involvement in the stabilization of microtubules and regulation of the mitotic spindle, which are crucial for proper chromosomal segregation during cell division. The knockout of this gene leads to altered cellular dynamics, providing a foundational tool for investigating its role in cancer biology and other diseases linked to cell cycle dysregulation. These cell lines serve as an invaluable resource in both basic and applied research, enabling scientists to elucidate the gene's mechanisms and its potential as a therapeutic target.
In terms of scientific significance, DLGAP5 Gene Knockout Cell Lines have extensive applications in cancer research, developmental biology, and pharmacological studies aimed at identifying novel treatment strategies. By understanding the pathways affected by DLGAP5 deletion, researchers can uncover insights into tumor progression and develop targeted therapies.
Compared to traditional methods of gene silencing such as RNA interference, these knockout cell lines provide a more stable and complete loss-of-function model, allowing for thorough characterization of biological phenomena without the variability associated with transient gene silencing techniques. This precision makes DLGAP5 cell lines a preferred choice for researchers seeking reliable and reproducible data.
For researchers and clinicians, the ability to investigate gene function and develop pivotal insights into disease mechanisms enhances the scientific exploration and innovation in personalized medicine. The DLGAP5 Gene Knockout Cell Lines represent a powerful tool in advancing biological understanding and therapeutic discovery.
Our company, with a robust background in genetic engineering and cellular research products, is committed to delivering high-quality biological tools that empower cutting-edge research and improve clinical outcomes, enabling researchers to maximize their potential for scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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