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DHX34 Knockout Cell Lines

Gene: DHX34

Official Full Name: DExH-box helicase 34provided by HGNC

Gene Summary: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. It is mapped to the glioma 19q tumor suppressor region and is a tumor suppressor candidate gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32884 DHX34 Knockout cell line (HeLa) Human DHX34 1:3~1:6 Negative Online Inquiry
KO32885 DHX34 Knockout cell line (HCT 116) Human DHX34 1:2~1:4 Negative Online Inquiry
KO32886 DHX34 Knockout cell line (HEK293) Human DHX34 1:3~1:6 Negative Online Inquiry
KO32887 DHX34 Knockout cell line (A549) Human DHX34 1:3~1:4 Negative Online Inquiry

Background

DHX34 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the DHX34 gene's role in cellular processes. Utilizing CRISPR/Cas9 technology, these cell lines exhibit a complete knockout of the DHX34 gene, allowing researchers to investigate the functional consequences of its absence in a controlled environment. The primary mechanism by which these cell lines operate is through targeted gene disruption, enabling precise manipulation of the genetic landscape to discern the implications of gene expression and regulation on various biological pathways.

The scientific importance of DHX34 Gene Knockout Cell Lines lies in their application in both research and clinical settings, specifically in the study of RNA metabolism and cellular stress responses. Given that DHX34 is implicated in various disease states, including cancer and neurodegenerative disorders, these cell lines offer significant insights into the molecular mechanisms at play. By providing a platform for functional assays, researchers can explore gene interactions, evaluate therapeutic targets, and advance the understanding of complex biological systems.

Compared to traditional gene alteration techniques, DHX34 Gene Knockout Cell Lines provide several advantages, including high efficiency, specificity, and ease of use. The CRISPR/Cas9 system not only allows for precise gene editing but also reduces the risks of off-target effects commonly associated with older methods. Furthermore, these cell lines can be readily utilized in high-throughput screening applications, making them indispensable tools for the drug discovery process.

Choosing DHX34 Gene Knockout Cell Lines empowers researchers and clinicians to dissect critical biological mechanisms and develop interventions based on genetic insights. The unparalleled accuracy and reliability offered by our product present a compelling case for its integration into cutting-edge research protocols. As a company with extensive experience in developing advanced genetic models, we are committed to providing high-quality biological products that advance scientific discovery and improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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