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DHRS4L2 Knockout Cell Lines

Gene: DHRS4L2

Official Full Name: dehydrogenase/reductase 4 like 2provided by HGNC

Gene Summary: This gene encodes a member of the short chain dehydrogenase reductase family. The encoded protein may be an NADPH dependent retinol oxidoreductase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27352 DHRS4L2 Knockout cell line (HeLa) Human DHRS4L2 1:3~1:6 Negative Online Inquiry
KO27353 DHRS4L2 Knockout cell line (HCT 116) Human DHRS4L2 1:2~1:4 Negative Online Inquiry
KO27354 DHRS4L2 Knockout cell line (HEK293) Human DHRS4L2 1:3~1:6 Negative Online Inquiry
KO27355 DHRS4L2 Knockout cell line (A549) Human DHRS4L2 1:3~1:4 Negative Online Inquiry

Background

DHRS4L2 Gene Knockout Cell Lines are specialized cellular models designed for the study of the DHRS4L2 gene, which is implicated in various metabolic processes and disease mechanisms. These cell lines have undergone targeted genetic modification, resulting in the complete knockout of the DHRS4L2 gene, facilitating the exploration of its physiological roles and contributions to biochemical pathways.

The key function of the DHRS4L2 knockout cell lines is to enable researchers to dissect the molecular functions associated with the loss of DHRS4L2 expression. Through these cellular models, scientists can examine alterations in metabolic activity, enzyme regulation, and cellular signaling pathways that are influenced by this gene's activity. By comparing phenotypic and molecular changes between wild-type and knockout cells, researchers can gain insights into the gene's role in various biological contexts, including its potential involvement in metabolic disorders and cancer.

The scientific importance of these knockout cell lines lies in their ability to provide a platform for validation of therapeutic targets and the development of novel intervention strategies in both research and clinical settings. They can be pivotal in drug discovery processes, aiding in the identification and characterization of compounds that may modulate the pathways influenced by DHRS4L2, further contributing to understanding diseases at a molecular level.

What sets DHRS4L2 gene knockout cell lines apart from alternative models is their specificity and precision, ensuring that the gene of interest is effectively disrupted, allowing for detailed functional studies. Unlike conventional knockdown methods, which may result in partial reductions of gene expression, these knockout cell lines provide a complete absence of DHRS4L2 activity, offering clearer insights into the gene's significance.

For researchers and clinicians, the value of using DHRS4L2 gene knockout cell lines extends beyond basic research; they serve as an essential tool for the elucidation of disease mechanisms, potentially leading to innovative therapies and improved patient outcomes. The use of these models accelerates the understanding of complex biological systems, making them an invaluable asset in translational science.

Our company specializes in the development and provision of high-quality biological products, leveraging cutting-edge gene editing technologies and expertise in cellular biology. By choosing our DHRS4L2 gene knockout cell lines, you are partnering with a leader committed to advancing scientific innovation and discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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