Gene: DENND2C
Official Full Name: DENN domain containing 2Cprovided by HGNC
Gene Summary: Enables guanyl-nucleotide exchange factor activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18331 | DENND2C Knockout cell line (HeLa) | Human | DENND2C | 1:3~1:6 | Negative | Online Inquiry |
KO18332 | DENND2C Knockout cell line (HCT 116) | Human | DENND2C | 1:2~1:4 | Negative | Online Inquiry |
KO18333 | DENND2C Knockout cell line (HEK293) | Human | DENND2C | 1:3~1:6 | Negative | Online Inquiry |
DENND2C Gene Knockout Cell Lines are specialized cellular models engineered to disable the expression of the DENND2C gene, which is critical in various cellular processes, including vesicle transport and cellular signaling pathways. By employing CRISPR-Cas9 technology, these knockout cell lines facilitate the study of the biological function of DENND2C and its involvement in health and disease states. The elimination of this gene allows researchers to observe resultant phenotypic changes, thereby offering insights into the gene’s role in cellular dynamics and potential pathological conditions, such as cancer or neurodegenerative diseases.
The primary function of DENND2C Gene Knockout Cell Lines lies in their ability to create a controlled environment for investigating gene function and the effects of its absence. By utilizing these cell lines in experiments, researchers can assess alterations in cellular behavior, signaling pathways, and gene expression profiles, paving the way for a deeper understanding of the molecular mechanisms underpinning various diseases. The precise deletion of the DENND2C gene allows for rigorous examination of gene-environment interactions and contributes to the growing field of functional genomics.
The scientific importance of these cell lines cannot be overstated; they provide invaluable tools for both basic and translational research. In clinical settings, they can be harnessed to identify potential therapeutic targets and to screen compounds that may reverse the effects of DENND2C deficiency. Moreover, their application can extend to high-throughput drug screening and mechanistic studies of drug action, thereby enhancing drug development processes.
Compared to alternative approaches, such as siRNA-mediated knockdown, DENND2C Gene Knockout Cell Lines offer a more stable and permanent solution to gene disruption. This stability enables longer-term experiments and better reproducibility of results, which are critical in both academic and industry research settings. Furthermore, the precise nature of CRISPR-Cas9 gene editing ensures a high specificity of knockout, minimizing off-target effects associated with earlier gene silencing techniques.
For researchers and clinicians, the value of DENND2C Gene Knockout Cell Lines lies in their potential to uncover new avenues for therapeutic intervention and to advance the understanding of complex biological systems. The ability to model specific genetic conditions provides a unique opportunity to translate fundamental research into clinical applications that can ultimately benefit patient care.
Our company, with its commitment to advancing biological research through innovative products, has developed these cell lines with the highest standards of quality and efficacy. We strive to support the scientific community by offering reliable tools that enhance research outcomes and foster breakthroughs in understanding genetic diseases.
Please note that all services are for research use only. Not intended for any clinical use.
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