Gene: DDN
Official Full Name: dendrinprovided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in cell projection and cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29855 | DDN Knockout cell line (HCT 116) | Human | DDN | 1:2~1:4 | Negative | Online Inquiry |
KO29856 | DDN Knockout cell line (HEK293) | Human | DDN | 1:3~1:6 | Negative | Online Inquiry |
DDN Gene Knockout Cell Lines are advanced cellular models designed to facilitate the functional analysis of specific genes by knocking out their expression. This innovative tool leverages state-of-the-art genome-editing techniques to create precise mutations, thereby allowing researchers to study gene function, analyze disease mechanisms, and assess therapeutic targets in a controlled laboratory environment.
The key function of DDN Gene Knockout Cell Lines lies in their ability to provide researchers with a streamlined approach to gene disruption. By utilizing CRISPR-Cas9 technology or similar methodologies, these cell lines effectively eliminate specific genetic sequences, allowing for adult or embryonic stem cell studies in various contexts. This innovative mechanism enables scientists to investigate the resulting phenotypic changes, cellular pathways, and potential compensatory mechanisms, leading to comprehensive insights into gene roles and their implications in biological processes.
The scientific importance of gene knockout cell lines is profound, offering robust applications in both research and clinical settings. They are indispensable in drug development, enabling the identification of actionable pathways for therapeutic intervention. Furthermore, they are routinely employed in cancer research, neurobiology, and developmental biology, where understanding gene function is critical. These models drive innovation in precision medicine by elucidating the genetic underpinnings of various diseases, which can lead to pioneering treatments and interventions.
When compared to alternative models like traditional knockdown techniques or random mutagenesis, DDN Gene Knockout Cell Lines provide unmatched specificity and efficiency. Their targeted approach minimizes off-target effects that can confound experimental outcomes, ensuring that researchers can confidently attribute observed phenotypes to the intended genetic alterations. These cell lines are designed for versatility and ease of use, compatible with various host cell types, thus accommodating a wide array of research disciplines.
For researchers and clinicians focused on advancing their scientific inquiries, DDN Gene Knockout Cell Lines offer a critical advantage—translating genetic insights into actionable knowledge. Their precise knockouts enhance the accuracy of experimental results, making them invaluable for studies that require a high level of precision and reproducibility.
Our company specializes in developing innovative biological products that empower researchers to drive forward their scientific endeavors. With a commitment to excellence and a thorough understanding of genetics, we are dedicated to providing high-quality tools like DDN Gene Knockout Cell Lines, fostering a deeper understanding of gene function and its implications in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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