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DDHD2 Knockout Cell Lines

Gene: DDHD2

Official Full Name: DDHD domain containing 2provided by HGNC

Gene Summary: This gene encodes a phospholipase enzyme containing sterile-alpha-motif (SAM), WWE, and DDHD domains. This protein participates in membrane trafficking between the endoplastic reticulum and the Golgi body. Mutations in this gene can cause autosomal recessive spastic paraplegia 54. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29583 DDHD2 Knockout cell line (HeLa) Human DDHD2 1:3~1:6 Negative Online Inquiry
KO29584 DDHD2 Knockout cell line (HCT 116) Human DDHD2 1:2~1:4 Negative Online Inquiry
KO29585 DDHD2 Knockout cell line (HEK293) Human DDHD2 1:3~1:6 Negative Online Inquiry
KO29586 DDHD2 Knockout cell line (A549) Human DDHD2 1:3~1:4 Negative Online Inquiry

Background

DDHD2 Gene Knockout Cell Lines represent a cutting-edge advancement in the field of genetic research and cellular biology, specifically engineered to facilitate in-depth study of the DDHD2 gene’s functions. These cell lines are created through the precise technique of CRISPR-Cas9 gene editing, resulting in the complete absence of the DDHD2 gene, allowing researchers to observe the consequential effects on cellular pathways and functions. The knockout mechanism is pivotal for elucidating gene function, mechanistic studies of disease models, and drug response evaluations.

The primary function of these cell lines is to serve as a rigorously controlled platform for understanding the role of DDHD2 in various biological processes, including lipid metabolism, cell signaling, and cellular integrity. By knocking out this specific gene, researchers can delineate the pathways it influences, contributing to a richer understanding of related biological phenomena, such as the pathophysiology of neurodegenerative diseases where DDHD2 has been implicated.

The scientific importance of DDHD2 Gene Knockout Cell Lines extends to both academic research and clinical applications. These models can be crucial for identifying potential therapeutic targets, validating drug candidates, and performing high-throughput screening assays. Furthermore, the unique insights gained from using these cells can significantly accelerate the translation of findings from bench to bedside.

Compared to other gene knockout approaches, our DDHD2 Gene Knockout Cell Lines offer superior specificity and efficiency, ensuring that the gene editing is precise and reproducible. This reliability is pivotal for maximizing experimental validity and minimizing off-target effects, thereby enhancing the overall quality of research outcomes.

For researchers and clinicians alike, the value of DDHD2 Gene Knockout Cell Lines lies in their ability to underpin meaningful discoveries that may lead to novel therapeutic strategies. Leveraging our extensive expertise in genetic engineering and cellular biology, our company is committed to providing high-quality biological products that empower the scientific community to advance their research objectives efficiently and effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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