Gene: DCP1A
Official Full Name: decapping mRNA 1Aprovided by HGNC
Gene Summary: Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP00194 | DCP1A gRNA1-gRNA2 KO plasmid | DCP1A | $850 | |||
KO00581 | DCP1A Knockout cell line(Huh-7) | Human | DCP1A | 1:2~1:3 | Negative | Online Inquiry |
KO06010 | DCP1A Knockout cell line (HeLa) | Human | DCP1A | 1:3~1:6 | Negative | Online Inquiry |
KO06011 | DCP1A Knockout cell line (HCT 116) | Human | DCP1A | 1:2~1:4 | Negative | Online Inquiry |
KO06012 | DCP1A Knockout cell line (HEK293) | Human | DCP1A | 1:3~1:6 | Negative | Online Inquiry |
KO06013 | DCP1A Knockout cell line (A549) | Human | DCP1A | 1:3~1:4 | Negative | Online Inquiry |
DCP1A Gene Knockout Cell Lines are specialized cell line models generated to study the functional consequences of the DCP1A gene, which encodes a decapping enzyme involved in the regulation of mRNA turnover. These cell lines are engineered through state-of-the-art CRISPR/Cas9 gene-editing technology, resulting in the precise disruption of the DCP1A gene. By creating a knockout model, researchers gain invaluable insights into the pathways and processes influenced by DCP1A, especially in the context of mRNA stability and gene expression regulation.
The primary function of these knockout cell lines is to facilitate the examination of mRNA metabolism, specifically the decapping and degradation processes in cellular environments. The absence of DCP1A allows for an in-depth analysis of the impact of mRNA decapping on cellular signaling, stress response, and overall gene expression patterns. Furthermore, by utilizing these models, scientists can investigate the potential roles of DCP1A in various diseases, including cancer and neurodegenerative disorders where altered mRNA turnover is a contributing factor.
The scientific importance of DCP1A Gene Knockout Cell Lines is underscored by their applications in both basic and applied research. They serve as vital tools for understanding physiological and pathological conditions, making them useful for drug discovery, functional genomics, and therapeutic interventions targeting mRNA metabolism.
Compared to alternative models, these knockout cell lines offer specificity, reproducibility, and robust data, minimizing the variability often encountered in traditional methods. Additionally, their tailored nature allows researchers to study the effects of DCP1A depletion unequivocally, providing clearer insights into the gene's contributions to cellular function.
For researchers and clinicians alike, the DCP1A Gene Knockout Cell Lines represent a significant advancement in molecular biology tools, enabling the exploration of mRNA dynamics with exceptional precision. Leveraging our extensive expertise in cellular engineering and genomics, our company is proud to offer these advanced cell lines that push the boundaries of research in gene function and therapeutic discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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