Gene: DCHS1
Official Full Name: dachsous cadherin-related 1provided by HGNC
Gene Summary: This gene is a member of the cadherin superfamily whose members encode calcium-dependent cell-cell adhesion molecules. The encoded protein has a signal peptide, 27 cadherin repeat domains and a unique cytoplasmic region. This particular cadherin family member is expressed in fibroblasts but not in melanocytes or keratinocytes. The cell-cell adhesion of fibroblasts is thought to be necessary for wound healing. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33988 | DCHS1 Knockout cell line (HEK293) | Human | DCHS1 | 1:3~1:6 | Negative | Online Inquiry |
DCHS1 Gene Knockout Cell Lines are specifically engineered cell lines where the DCHS1 gene has been inactivated, providing researchers with a powerful tool for studying gene function and related pathways in various biological contexts. DCHS1, known for its role in cellular adhesion and signaling, is integral in processes such as tissue development and maintenance. The knockout of this gene enables scientists to investigate its impact on cellular behavior, including proliferation, differentiation, and the integrity of cell junctions.
The primary function of the DCHS1 Gene Knockout Cell Lines lies in their ability to model diseases associated with DCHS1 dysfunction and to elucidate the molecular mechanisms underlying these conditions. By observing the physiological and biochemical changes in these cell lines, researchers can derive insights into the critical roles of DCHS1 in cardiovascular development and other physiological processes. This is particularly crucial for understanding disorders where cellular adhesion plays a significant role.
In terms of scientific importance, these knockout cell lines present invaluable applications in both research and clinical settings. They facilitate drug screening, enabling the identification of therapeutic compounds that can target pathways modulated by DCHS1. Furthermore, they are essential for the basic research community, providing a clearer understanding of gene interactions within complex biological systems.
Compared to alternative gene knockout models, DCHS1 Gene Knockout Cell Lines are distinguished by their high specificity and reliability, enhancing reproducibility in experimental outcomes. Our product is rigorously validated for consistency, ensuring that researchers receive a reliable platform for their studies.
For researchers and clinicians seeking to advance their understanding of cellular interactions and disease mechanisms, DCHS1 Gene Knockout Cell Lines represent a valuable asset. The unique insights gained from these models can lead to breakthroughs in therapeutic strategies for diseases impacting cellular adhesion and development.
Our company prides itself on producing high-quality biological products backed by extensive research and commitment to innovation, ensuring scientists have the tools necessary for their groundbreaking work.
Please note that all services are for research use only. Not intended for any clinical use.
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