Gene: DCAF4L1
Official Full Name: DDB1 and CUL4 associated factor 4 like 1provided by HGNC
Gene Summary: Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18403 | DCAF4L1 Knockout cell line (HCT 116) | Human | DCAF4L1 | 1:2~1:4 | Negative | Online Inquiry |
DCAF4L1 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate the study of the DCAF4L1 gene's role in cellular processes and disease states. By utilizing the CRISPR-Cas9 genome editing technique, these cell lines are created to lack the DCAF4L1 gene, allowing researchers to investigate the gene's function in a controlled environment. The knockout approach enables the elucidation of its impact on pathways involved in cell signaling, proliferation, and response to external stimuli, thereby providing a comprehensive understanding of the gene's biological significance.
The key mechanism underlying the DCAF4L1 knockout is the targeted disruption of the gene's coding sequence, which results in a loss of protein expression. This allows for the assessment of phenotypic changes in various experimental contexts, such as drug response and cellular stress, making these cell lines invaluable tools in both basic research and drug development programs. Scientists can use this model to investigate potential therapeutic strategies for diseases where DCAF4L1 is implicated, including cancer and metabolic disorders.
The scientific importance of DCAF4L1 Gene Knockout Cell Lines extends beyond basic research; they serve crucial roles in evaluating gene function, validating drug targets, and screening potential therapeutics. Compared to conventional cell lines, the specificity of gene knockout provides a clearer view of the effects mediated by the absence of the DCAF4L1 gene, making it a superior alternative for research involving genetic manipulation.
By incorporating DCAF4L1 knockout models into their studies, researchers and clinicians can gain deeper insights into gene function and regulatory pathways, ultimately driving innovations in treatment and intervention strategies. Additionally, the high-quality, reproducible nature of these cell lines, along with our rigorous validation protocols, ensures researchers can trust the data generated from using these models.
Our company specializes in creating expertly validated biological products tailored for cutting-edge research. With a particular focus on genetic manipulation tools, we provide researchers with the resources they need to explore and understand complex biological interactions effectively. Choosing our DCAF4L1 Gene Knockout Cell Lines empowers your research, helping you stay at the forefront of scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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