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DCAF10 Knockout Cell Lines

Gene: DCAF10

Official Full Name: DDB1 and CUL4 associated factor 10provided by HGNC

Gene Summary: Predicted to be involved in protein ubiquitination. Part of Cul4-RING E3 ubiquitin ligase complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18395 DCAF10 Knockout cell line (HeLa) Human DCAF10 1:3~1:6 Negative Online Inquiry
KO18396 DCAF10 Knockout cell line (HCT 116) Human DCAF10 1:2~1:4 Negative Online Inquiry
KO18397 DCAF10 Knockout cell line (HEK293) Human DCAF10 1:3~1:6 Negative Online Inquiry
KO18398 DCAF10 Knockout cell line (A549) Human DCAF10 1:3~1:4 Negative Online Inquiry

Background

DCAF10 Gene Knockout Cell Lines are genetically engineered models that feature targeted deletions of the DCAF10 gene, a crucial component known to mediate various cellular processes, including protein degradation and response to stressors. These knockout cell lines are instrumental in elucidating the gene's function and its role in cellular homeostasis and signaling pathways.

The key function of DCAF10 in cellular mechanics revolves around its role as a substrate receptor for the Cullin-RING E3 ubiquitin ligase complex, which tags proteins for degradation via the ubiquitin-proteasome pathway. By selectively knocking out the DCAF10 gene, researchers can study the impact of its absence on cellular proliferation, apoptosis, and overall functionality, thus providing valuable insights into various disease models, including cancer and other disorders characterized by dysregulated protein homeostasis.

The scientific importance of DCAF10 Gene Knockout Cell Lines lies in their applications across multiple research domains, such as cancer biology, immunology, and pharmacology. These models facilitate the investigation of therapeutic targets and the development of novel pharmacological agents. Furthermore, they are particularly valuable in drug discovery processes, enabling researchers to assess the effects of candidate compounds in a controlled environment devoid of the confounding influences of the DCAF10 protein.

What sets our DCAF10 Gene Knockout Cell Lines apart from alternatives is the precision of gene editing and validation techniques employed in their creation, ensuring a stable and reproducible genetic alteration. This level of specificity minimizes off-target effects, ultimately increasing the reliability of experimental results.

For researchers and clinicians, these knockout cell lines represent a critical tool for expanding our understanding of complex biological systems and potential treatment avenues. They not only enhance experimental rigor but also provide a powerful framework for translating basic research into clinical applications.

As an industry leader in producing high-quality biological research products, our company prides itself on its expertise and commitment to supporting the scientific community with robust, reliable tools that advance research and therapeutic innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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