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DAPK3 Knockout Cell Lines

Gene: DAPK3

Official Full Name: death associated protein kinase 3provided by HGNC

Gene Summary: Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells. These results suggest that DAPK3 may play a role in the induction of apoptosis. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38296 DAPK3 Knockout cell line (HeLa) Human DAPK3 1:3~1:6 Negative Online Inquiry
KO38297 DAPK3 Knockout cell line (HCT 116) Human DAPK3 1:2~1:4 Negative Online Inquiry
KO38298 DAPK3 Knockout cell line (HEK293) Human DAPK3 1:3~1:6 Negative Online Inquiry
KO38299 DAPK3 Knockout cell line (A549) Human DAPK3 1:3~1:4 Negative Online Inquiry

Background

DAPK3 Gene Knockout Cell Lines are genetically modified cell lines created to lack the expression of the Death-Associated Protein Kinase 3 (DAPK3) gene. DAPK3 is a crucial serine/threonine kinase implicated in various cellular processes, including apoptosis, autophagy, and response to cellular stress. The knockout of this gene allows researchers to investigate the specific functions and roles that DAPK3 plays in different physiological and pathological conditions.

These cell lines operate by using CRISPR/Cas9 technology or similar gene-editing techniques to induce targeted deletions in the DAPK3 gene, effectively preventing any functional protein from being produced. This enables researchers to delineate the pathways influenced by DAPK3 and to assess its contributions to tumorigenesis, neurodegenerative disorders, and immune responses, among others. By observing the functional changes in these knockout cell lines compared to wild-type controls, scientists can elucidate the physiological relevance of DAPK3, providing deeper insights into potential therapeutic targets.

The scientific importance of DAPK3 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. In disease modeling, these cell lines serve as invaluable tools for understanding the underlying mechanisms of diseases linked to DAPK3 aberrations. Moreover, their utility in drug development and screening can aid in identifying novel compounds that modulate DAPK3-related pathways, offering solutions for treating conditions influenced by this kinase.

What sets our DAPK3 Gene Knockout Cell Lines apart is the high efficiency of gene editing, consistent quality across batches, and in-depth characterization to confirm the knockout status. These features ensure reliable results, which are critical for obtaining reproducible and valid data. Additionally, our cell lines are provided with comprehensive user support and detailed experimental protocols, enhancing the research experience for scientists.

For researchers and clinicians committed to advancing the frontiers of knowledge in cell biology and disease mechanisms, investing in DAPK3 Gene Knockout Cell Lines represents a strategic choice. Our company specializes in providing high-quality biological products grounded in rigorous scientific research, ensuring that our offerings meet the dynamic needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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