Gene: CYBC1
Official Full Name: cytochrome b-245 chaperone 1provided by HGNC
Gene Summary: Involved in innate immune response and respiratory burst after phagocytosis. Located in endoplasmic reticulum. Implicated in autosomal recessive chronic granulomatous disease 5. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO18457 | CYBC1 Knockout cell line (HeLa) | Human | CYBC1 | 1:3~1:6 | Negative | Online Inquiry |
KO18458 | CYBC1 Knockout cell line (HCT 116) | Human | CYBC1 | 1:2~1:4 | Negative | Online Inquiry |
KO18459 | CYBC1 Knockout cell line (HEK293) | Human | CYBC1 | 1:3~1:6 | Negative | Online Inquiry |
KO18460 | CYBC1 Knockout cell line (A549) | Human | CYBC1 | 1:3~1:4 | Negative | Online Inquiry |
CYBC1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to study the functional role of the CYBC1 gene, known to be involved in key biological processes such as apoptosis and cell cycle regulation. This product features a robust CRISPR-Cas9 gene editing technology that allows for precise disruption of the CYBC1 locus, resulting in a complete knockout of gene expression. Researchers can utilize these cell lines to better understand the implications of CYBC1 in various physiological and pathological contexts, including cancer and neurodegenerative diseases.
The primary mechanism at work involves the introduction of guide RNAs targeting the CYBC1 gene, which directs the Cas9 nuclease to create double-stranded breaks. This leads to errors in repair when the cellular repair mechanisms attempt to fix the break, ultimately resulting in frameshift mutations that disrupt the gene's function. The CYBC1 Knockout Cell Lines serve as a valuable tool for elucidating the gene's involvement in cellular signaling pathways and its contribution to disease mechanisms.
From a scientific perspective, these cell lines have significant applications in basic research, drug development, and gene therapy studies. By providing a model system to assess the phenotypic effects of CYBC1 loss, they facilitate the exploration of potential therapeutic targets and biomarkers. Additionally, these knockout models help in validating high-throughput screening assays, paving the way for novel drug discovery.
What sets CYBC1 Gene Knockout Cell Lines apart from alternative products on the market is their high specificity and consistency in gene disruption, combined with the ease of use offered by our detailed protocols. These lines come validated for numerous applications, ensuring reliable results in research settings.
For researchers and clinicians seeking to advance their understanding of gene function within crucial biological pathways, CYBC1 Gene Knockout Cell Lines represent an invaluable asset. Our commitment to quality and innovation is underscored by our expansive expertise in genetic engineering and cell culture technologies, providing researchers with unparalleled support and resources for their studies.
Please note that all services are for research use only. Not intended for any clinical use.
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