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CYB5RL Knockout Cell Lines

Gene: CYB5RL

Official Full Name: cytochrome b5 reductase likeprovided by HGNC

Gene Summary: Predicted to enable cytochrome-b5 reductase activity, acting on NAD(P)H. Predicted to be involved in bicarbonate transport. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18465 CYB5RL Knockout cell line (HeLa) Human CYB5RL 1:3~1:6 Negative Online Inquiry
KO18466 CYB5RL Knockout cell line (HCT 116) Human CYB5RL 1:2~1:4 Negative Online Inquiry
KO18467 CYB5RL Knockout cell line (HEK293) Human CYB5RL 1:3~1:6 Negative Online Inquiry
KO18468 CYB5RL Knockout cell line (A549) Human CYB5RL 1:3~1:4 Negative Online Inquiry

Background

CYB5RL Gene Knockout Cell Lines are genetically engineered cell models designed to lack the cytochrome b5 reductase-like protein 1 gene (CYB5RL). This gene plays a significant role in various biochemical pathways, including electron transport and drug metabolism. By knocking out CYB5RL, these cell lines facilitate the examination of its cellular functions and the implications of its absence in physiological and pathological contexts.

The primary function of CYB5RL is to participate in redox reactions, which are crucial for maintaining cellular homeostasis and modulating oxidative stress. The knockout of this gene alters cellular responses to stress and influences metabolic pathways, allowing researchers to dissect its role in conditions such as cancer, cardiovascular diseases, and metabolic syndromes. Mechanistically, the absence of CYB5RL can provide insights into the adaptive response of cells to varying conditions and reveal how similar mechanisms may be exploited in targeted therapies.

In terms of scientific importance, these knockout cell lines serve as invaluable tools in both research and clinical settings. They provide a model to study gene function, assess drug interactions, and evaluate biological responses, significantly accelerating the understanding of complex diseases. Moreover, CYB5RL Gene Knockout Cell Lines enable high-throughput screening for novel pharmacological agents and can play a pivotal role in personalized medicine by elucidating patient-specific drug responses.

What sets these cell lines apart from conventional alternatives is their specificity and precision. Unlike standard cell lines that may express varied levels of CYB5RL, our knockout cell lines are rigorously validated to ensure a complete absence of the target gene, providing a reliable platform for experimentation. This high level of specificity reduces background noise and enhances the reproducibility of results, making it an attractive choice for researchers focused on gene function.

For researchers and clinicians aiming to deepen their understanding of cellular processes and develop innovative therapies, CYB5RL Gene Knockout Cell Lines offer a unique and effective approach. With our commitment to scientific excellence and innovation, we provide high-quality biological products tailored to meet the demanding needs of the research community. Our expertise in genetic engineering ensures that you receive robust and well-characterized cell lines that can help pave the way for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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