Gene: CTHRC1
Official Full Name: collagen triple helix repeat containing 1provided by HGNC
Gene Summary: This locus encodes a protein that may play a role in the cellular response to arterial injury through involvement in vascular remodeling. Mutations at this locus have been associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05256 | CTHRC1 Knockout cell line (HCT 116) | Human | CTHRC1 | 1:2~1:4 | Negative | Online Inquiry |
KO05257 | CTHRC1 Knockout cell line (A549) | Human | CTHRC1 | 1:3~1:4 | Negative | Online Inquiry |
CTHRC1 Gene Knockout Cell Lines are genetically modified cellular models characterized by the homozygous deletion of the CTHRC1 gene, which has been identified as a critical regulator of various biological processes, including cell proliferation, migration, and differentiation. These cell lines serve as versatile tools for molecular and cellular biology research, allowing scientists to investigate the effects of CTHRC1 deficiency on cellular function and signaling pathways. By utilizing CRISPR/Cas9 technology, CTHRC1 gene knockout cell lines provide a reliable and efficient means to study gene function and contribute to the elucidation of complex biological mechanisms.
The key functionality of the CTHRC1 gene knockout lies in its ability to simulate loss-of-function conditions, thus enabling researchers to explore how the absence of CTHRC1 influences cellular behavior. These cell lines can be employed in various experiments, including cancer research, where CTHRC1 has been implicated in tumor progression and metastasis. Additionally, they are valuable for studying wound healing, angiogenesis, and fibrosis, as CTHRC1 plays a pivotal role in tissue remodeling processes.
The scientific importance of these cell lines emerges from their potential to advance our understanding of CTHRC1's role in disease mechanisms, particularly in cancer and fibrotic diseases. Their applications extend beyond basic research; they can also be pivotal in developing therapeutic strategies targeting CTHRC1-associated pathways, thus translating insights into clinical solutions.
One significant advantage of CTHRC1 Gene Knockout Cell Lines over conventional cell lines is their precise genetic modification, which enhances specificity and reproducibility when investigating gene function. Additionally, these cell lines are crafted for easy adaptation to various experimental setups, making them accessible for both in vitro and in vivo studies.
For researchers and clinicians, the exploration of CTHRC1 through these knockout cell lines presents an invaluable opportunity to gain deeper insights into pathological conditions and develop targeted therapies. With our commitment to delivering high-quality, scientifically validated products, our company provides a suite of biologically relevant tools that empower the scientific community to drive advancement in understanding diseases and improving patient outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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