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CSRP2 Knockout Cell Lines

Gene: CSRP2

Official Full Name: cysteine and glycine rich protein 2provided by HGNC

Gene Summary: CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04209 CSRP2 Knockout cell line (HeLa) Human CSRP2 1:3~1:6 Negative Online Inquiry
KO04210 CSRP2 Knockout cell line (HCT 116) Human CSRP2 1:2~1:4 Negative Online Inquiry
KO04211 CSRP2 Knockout cell line (HEK293) Human CSRP2 1:3~1:6 Negative Online Inquiry
KO04212 CSRP2 Knockout cell line (A549) Human CSRP2 1:3~1:4 Negative Online Inquiry

Background

CSRP2 Gene Knockout Cell Lines are meticulously engineered cellular models designed to facilitate the study of the CSRP2 gene's role in cellular mechanisms and disease pathology. Through the precise removal of the CSRP2 gene, these knockout cell lines enable researchers to dissect the gene’s functional contributions to biological processes such as muscle differentiation, cell signaling, and stress responses.

The fundamental mechanism involves utilizing CRISPR-Cas9 technology, which allows for targeted gene editing, leading to the specific disruption of CSRP2 expression. This loss of function is critical for elucidating the pathways in which CSRP2 is implicated, particularly in muscle-related disorders and cardiovascular diseases. The knockout cell lines serve as an invaluable tool for investigating gene functions, drug discovery, and validation of therapeutic targets.

Scientifically, these CSRP2 knockout models are particularly significant in research settings focused on muscle biology, regenerative medicine, and cellular responses to physiological stress. By providing a reliable and reproducible system for loss-of-function studies, these cell lines offer a platform for advancing understanding in areas such as hypertrophy, atrophy, and tissue engineering.

Compared to other gene manipulation techniques, such as RNA interference, CSRP2 Gene Knockout Cell Lines provide permanent and precise genetic modifications, ensuring sustained gene disruption. This advantage grants researchers greater confidence in their experimental results and facilitates more rigorous investigation into the CSRP2 gene's functions.

For researchers and clinicians, the value of these knockout cell lines lies in their potential to unlock new discoveries related to muscle and cardiovascular health, paving the way for innovative therapies and advancing personalized medicine. Our company stands at the forefront of genetic engineering, offering robust and high-quality products that empower scientific inquiry and foster breakthroughs in biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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