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CROCC Knockout Cell Lines

Gene: CROCC

Official Full Name: ciliary rootlet coiled-coil, rootletinprovided by HGNC

Gene Summary: Predicted to enable kinesin binding activity and structural molecule activity. Involved in several processes, including centriole-centriole cohesion; positive regulation of cilium assembly; and positive regulation of protein localization to cilium. Located in cytoskeleton; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32896 CROCC Knockout cell line (HeLa) Human CROCC 1:3~1:6 Negative Online Inquiry
KO32897 CROCC Knockout cell line (HCT 116) Human CROCC 1:2~1:4 Negative Online Inquiry
KO32898 CROCC Knockout cell line (HEK293) Human CROCC 1:3~1:6 Negative Online Inquiry
KO32899 CROCC Knockout cell line (A549) Human CROCC 1:3~1:4 Negative Online Inquiry

Background

CROCC Gene Knockout Cell Lines are genetically engineered cell lines that have undergone targeted gene disruption using advanced CRISPR-Cas9 technology. This process results in precise elimination of specific genes, allowing researchers to study the functional consequences of gene loss in a variety of biological contexts. The CROCC cell lines are designed to provide robust and reproducible models that facilitate the investigation of gene functions, protein interactions, and disease mechanisms.

The primary function of CROCC Gene Knockout Cell Lines lies in their ability to enable loss-of-function studies, which are pivotal for understanding gene roles in cellular pathways, metabolism, and development. Upon knockout of the target gene, these cell lines can be utilized to observe phenotypic changes, assess signaling pathways, and evaluate responses to various treatments. The precision of CRISPR-Cas9 technology ensures minimal off-target effects, thus providing reliable data essential for downstream applications.

Scientifically, these knockout cell lines are invaluable tools in molecular biology, drug discovery, and therapeutic development. Their applications range from basic research exploring gene function to clinical research aiming to identify potential therapeutic targets for diseases such as cancer, genetic disorders, and infectious diseases. Researchers can utilize these models to validate hypotheses and accelerate the translation of findings from bench to bedside.

CROCC Gene Knockout Cell Lines boast several advantages over traditional gene knockout methods, including faster generation times, enhanced specificity, and a wider range of customizable options. Unlike older approaches that relied on homologous recombination, the CRISPR-based methodology offers greater efficiency and accessibility for researchers, making it easier to create tailored models for diverse applications.

By choosing CROCC Gene Knockout Cell Lines, researchers and clinicians gain access to cutting-edge technology that drives innovation in their work. Our commitment to quality and rigor in product development ensures that each cell line meets the highest standards, providing users with the confidence needed to pursue their scientific inquiries. At CROCC, we specialize in delivering advanced biological research tools that empower discoveries and foster advancements in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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