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CRACD Knockout Cell Lines

Gene: CRACD

Official Full Name: capping protein inhibiting regulator of actin dynamicsprovided by HGNC

Gene Summary: Involved in negative regulation of barbed-end actin filament capping. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18553 CRACD Knockout cell line (HeLa) Human CRACD 1:3~1:6 Negative Online Inquiry
KO18554 CRACD Knockout cell line (HCT 116) Human CRACD 1:2~1:4 Negative Online Inquiry
KO18555 CRACD Knockout cell line (HEK293) Human CRACD 1:3~1:6 Negative Online Inquiry

Background

CRACD Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the CRACD gene (calcium release-activated calcium modulator 1), which has significant roles in calcium signaling pathways. These knockout cell lines enable researchers to comprehensively investigate the biological consequences of CRACD deficiency and its implications in various physiological and pathological processes, including immune response, muscle contraction, and potential cancer pathways.

The primary function of these cell lines lies in their ability to model the effects of CRACD disruption on cellular functions by elucidating calcium signaling mechanisms. CRACD is pivotal in regulating calcium influx into cells, thus influencing a myriad of downstream signaling cascades. By utilizing these knockout models, researchers can explore altered pathways in cellular proliferation, differentiation, apoptosis, and immune function, thereby providing insights into diseases linked to aberrant calcium signaling.

The scientific importance of CRACD Gene Knockout Cell Lines extends to their utility in both fundamental research and clinical applications. They are essential tools for studying calcium signaling disorders and developing targeted therapeutic strategies. Additionally, these cell lines can be used in drug discovery processes to evaluate the efficacy of new compounds aimed at restoring normal cellular functions in conditions affected by CRACD mutations.

What sets CRACD Gene Knockout Cell Lines apart from other models is their specificity and reliability. Unlike traditional methods that may only partially replicate gene function, these genetically modified lines offer a precise way to study the complete absence of CRACD, leading to more accurate experimental outcomes. Their robust reproducibility and compatibility with a variety of experimental setups make them indispensable for modern biological research.

For researchers and clinicians alike, CRACD Gene Knockout Cell Lines offer invaluable insights that can enhance understanding of disease mechanisms and pave the way for innovative therapeutic options. Our company is committed to providing high-quality biological products, backed by a team of experts dedicated to supporting your research needs with precision-engineered solutions tailored for advanced scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

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