Gene: CRABP2
Official Full Name: cellular retinoic acid binding protein 2provided by HGNC
Gene Summary: This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38433 | CRABP2 Knockout cell line (HeLa) | Human | CRABP2 | 1:3~1:6 | Negative | Online Inquiry |
KO38434 | CRABP2 Knockout cell line (HCT 116) | Human | CRABP2 | 1:2~1:4 | Negative | Online Inquiry |
KO38435 | CRABP2 Knockout cell line (HEK293) | Human | CRABP2 | 1:3~1:6 | Negative | Online Inquiry |
KO38436 | CRABP2 Knockout cell line (A549) | Human | CRABP2 | 1:3~1:4 | Negative | Online Inquiry |
CRABP2 Gene Knockout Cell Lines are specialized, genetically engineered cell lines designed to study the functions and implications of the Cellular Retinoic Acid-Binding Protein 2 (CRABP2) gene. By utilizing CRISPR-Cas9 gene-editing technology, these cell lines exhibit a complete knockout of the CRABP2 gene, thereby enabling researchers to investigate the role that CRABP2 plays in cell differentiation, proliferation, and retinoic acid signaling pathways.
The primary function of the CRABP2 gene involves the regulation of retinoic acid, which is crucial for various biological processes, including embryonic development and cellular growth. By creating CRABP2 knockout cell lines, researchers can elucidate the mechanisms through which CRABP2 influences retinoic acid availability and activity, thereby gaining insights into diseases related to retinoid dysregulation, such as certain cancers and developmental disorders.
In both research and clinical settings, CRABP2 knockout cell lines serve as invaluable tools for drug discovery, toxicology assessments, and understanding the molecular basis of disorders associated with retinoid metabolism. Their application extends beyond basic research, offering potential for therapeutic advancements and understanding personalized medicine approaches.
One of the significant advantages of our CRABP2 Gene Knockout Cell Lines is the high efficiency of the knockout achieved through optimized CRISPR methodologies, ensuring reliability and reproducibility. Compared to other gene-editing methods, our product provides streamlined protocols that can save researchers time and resources, allowing for improved experimental throughput.
For researchers and clinicians aiming to deepen their understanding of CRABP2's role in health and disease, these knockout cell lines are an optimal choice. The inherent value lies in their capacity to provide clarity on the functional implications of CRABP2, paving the way for novel interventions and enhanced patient outcomes.
Our company specializes in the development of advanced biological products backed by rigorous research and development practices. We are committed to delivering high-quality tools that empower the scientific community in their quest to unravel complex biological processes.
Please note that all services are for research use only. Not intended for any clinical use.
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