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COMMD2 Knockout Cell Lines

Gene: COMMD2

Official Full Name: COMM domain containing 2provided by HGNC

Gene Summary: Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22998 COMMD2 Knockout cell line (HeLa) Human COMMD2 1:3~1:6 Negative Online Inquiry
KO22999 COMMD2 Knockout cell line (HCT 116) Human COMMD2 1:2~1:4 Negative Online Inquiry
KO23000 COMMD2 Knockout cell line (HEK293) Human COMMD2 1:3~1:6 Negative Online Inquiry
KO23001 COMMD2 Knockout cell line (A549) Human COMMD2 1:3~1:4 Negative Online Inquiry

Background

COMMD2 Gene Knockout Cell Lines represent a significant advancement in the field of molecular biology, specifically designed for researchers investigating the role of the COMM domain-containing protein 2 (COMMD2) in various biological processes. These genetically modified cell lines are engineered to lack the functional COMMD2 gene, providing a powerful tool for studying its contribution to cellular functions such as protein trafficking, inflammation responses, and regulation of gene expression.

The primary function of COMMD2 involves modulating the stability and degradation of various proteins and cellular signaling pathways. By introducing knockout strategies using methods such as CRISPR/Cas9, these cell lines enable researchers to dissect the molecular mechanisms by which COMMD2 influences cellular homeostasis and pathology, particularly in cancer and immune responses. The ability to observe phenotypic changes in COMMD2-depleted cells facilitates a deeper understanding of its roles in disease pathways, potentially leading to novel therapeutic interventions.

Scientifically, COMMD2 Gene Knockout Cell Lines are invaluable in both research and clinical settings. They are essential in high-throughput screening assays, drug discovery processes, and functional genomics studies. Their applications extend from basic research to translational medicine, providing insights into disease mechanisms that could inform treatment strategies for conditions associated with dysregulated COMMD2 activity.

What sets these knockout cell lines apart from traditional models is their specificity and precision in gene editing, leading to reproducible and reliable results. Unlike other methods that may produce variable outcomes, our COMMD2 Gene Knockout Cell Lines offer a standardized platform for experimental design, ensuring high data integrity across studies.

For researchers and clinicians seeking to understand the nuances of COMMD2's biological roles, these cell lines represent not just a product, but a pathway to groundbreaking research outcomes. The expertise behind this offering is rooted in our commitment to advancing genetic research tools and providing top-tier products that enhance scientific discovery. With a dedicated focus on quality and innovation, we empower the scientific community to expand the frontiers of knowledge in their respective fields.

Please note that all services are for research use only. Not intended for any clinical use.

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