Gene: CNTRL
Official Full Name: centriolinprovided by HGNC
Gene Summary: This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31267 | CNTRL Knockout cell line (HeLa) | Human | CNTRL | 1:3~1:6 | Negative | Online Inquiry |
KO31268 | CNTRL Knockout cell line (HCT 116) | Human | CNTRL | 1:2~1:4 | Negative | Online Inquiry |
KO31269 | CNTRL Knockout cell line (HEK293) | Human | CNTRL | 1:3~1:6 | Negative | Online Inquiry |
KO31270 | CNTRL Knockout cell line (A549) | Human | CNTRL | 1:3~1:4 | Negative | Online Inquiry |
CNTRL Gene Knockout Cell Lines are genetically modified cellular models designed to enable researchers to efficiently investigate the function of specific genes by creating a complete loss-of-function scenario. These cell lines utilize advanced CRISPR-Cas9 gene-editing technology to achieve precise deletions within the target gene sequences, facilitating comprehensive studies on gene expression, protein interactions, and cellular pathways.
The key function of CNTRL Gene Knockout Cell Lines lies in their ability to knock out genes with high specificity and efficiency, thereby providing a robust tool for functional genomics. The CRISPR-Cas9 system introduces double-strand breaks at targeted genomic locations, which are repaired through error-prone pathways leading to insertions or deletions that disrupt gene functionality. By employing these cell lines, scientists can elucidate gene functions, model diseases, and explore potential therapeutic targets in a controlled environment.
The scientific importance of CNTRL Gene Knockout Cell Lines is underscored by their vast applications in both fundamental research and clinical settings. They are instrumental in drug discovery, biomarker discovery, and the development of precision medicine by allowing for the identification of genetic contributors to diseases. Furthermore, these cell lines aid in understanding cellular responses to therapeutic agents and can be used for high-throughput screening processes.
Compared to traditional methods of gene knockout, CNTRL Gene Knockout Cell Lines offer several advantages, including increased targeting precision, reduced off-target effects, and shorter lead times in generating knockout models. This innovative approach allows researchers to save time and resources while enhancing experimental reproducibility and reliability.
For researchers and clinicians aiming to unlock the complexities of genetic regulation and disease mechanisms, CNTRL Gene Knockout Cell Lines represent a valuable asset, driving forward the frontiers of biomedical research. Our company prides itself on its extensive expertise in genetic engineering and offers a diverse portfolio of biological products tailored to meet the evolving needs of the scientific community. With our commitment to quality and innovation, we serve as a trusted partner in advancing research and therapeutic developments.
Please note that all services are for research use only. Not intended for any clinical use.
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