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CNTNAP3B Knockout Cell Lines

Gene: CNTNAP3B

Official Full Name: contactin associated protein family member 3Bprovided by HGNC

Gene Summary: Predicted to be involved in cell adhesion. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO18624 CNTNAP3B Knockout cell line (HeLa) Human CNTNAP3B 1:3~1:6 Negative Online Inquiry
KO18625 CNTNAP3B Knockout cell line (HCT 116) Human CNTNAP3B 1:2~1:4 Negative Online Inquiry
KO18626 CNTNAP3B Knockout cell line (HEK293) Human CNTNAP3B 1:3~1:6 Negative Online Inquiry
KO18627 CNTNAP3B Knockout cell line (A549) Human CNTNAP3B 1:3~1:4 Negative Online Inquiry

Background

CNTNAP3B Gene Knockout Cell Lines are specialized cellular models that have undergone a targeted genetic modification to disable the CNTNAP3B gene. This gene encodes for a member of the neurexin family of proteins, which are pivotal in establishing and maintaining synaptic functions within the nervous system. By rendering this gene inactive, the knockout cell lines offer researchers a powerful tool for exploring the intricate roles of CNTNAP3B in neurodevelopment and neuropsychiatric conditions.

The primary function of these cell lines is to elucidate the mechanisms by which CNTNAP3B influences neuronal connectivity, cell adhesion, and synapse formation. By manipulating these cells, scientists can investigate downstream signaling pathways and the impact of CNTNAP3B deficiency on cell behavior, allowing for a detailed exploration of molecular interactions in health and disease. Such knowledge is crucial for understanding the biochemical basis of disorders like autism spectrum disorder and schizophrenia, where anomalies in synaptic function are often implicated.

The scientific importance of CNTNAP3B Gene Knockout Cell Lines extends into both basic and translational research applications. They serve as indispensable models for drug screening and biomarker discovery, as well as facilitating the validation of therapeutic targets aimed at restoring normal synaptic activity in affected tissues. Compared to traditional models or alternative gene-editing methods, these knockout cell lines provide enhanced specificity and reproducibility, ensuring that experimental results are reliable and comparable across studies.

What sets our CNTNAP3B Gene Knockout Cell Lines apart from alternatives in the market is their high level of validation and characterization, ensuring that researchers can trust the integrity of the data generated. Additionally, they are complemented by a suite of supporting materials, including detailed background literature and protocols, facilitating immediate deployment in research settings.

Investing in CNTNAP3B Gene Knockout Cell Lines is invaluable for researchers and clinicians aiming to push the boundaries of neurobiology. By using these advanced models, users can contribute to a deeper understanding of neurological disorders, ultimately paving the way for innovative therapeutic strategies. Our company specializes in providing high-quality biological products tailored to meet the evolving needs of the scientific community, ensuring that our clients have access to reliable tools that empower groundbreaking research.

Please note that all services are for research use only. Not intended for any clinical use.

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