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CNNM1 Knockout Cell Lines

Gene: CNNM1

Official Full Name: cyclin and CBS domain divalent metal cation transport mediator 1provided by HGNC

Gene Summary: This gene encodes a member of the ancient conserved domain protein family. The encoded protein may bind copper. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28089 CNNM1 Knockout cell line (HeLa) Human CNNM1 1:3~1:6 Negative Online Inquiry
KO28090 CNNM1 Knockout cell line (HEK293) Human CNNM1 1:3~1:6 Negative Online Inquiry
KO28091 CNNM1 Knockout cell line (A549) Human CNNM1 1:3~1:4 Negative Online Inquiry

Background

CNNM1 Gene Knockout Cell Lines are innovative biological tools designed to facilitate research in cellular and molecular biology by targeting the CNNM1 gene, which plays a critical role in magnesium homeostasis and various cellular signaling pathways. These knockout cell lines are created using precise gene editing techniques, such as CRISPR/Cas9, to disrupt the expression of the CNNM1 gene, thereby allowing researchers to study its functional implications in both physiological and pathological contexts.

The primary mechanism by which these cell lines operate is through the introduction of mutations in the CNNM1 gene that lead to a loss of function. As a result, researchers can investigate the downstream effects of CNNM1 deficiency on cellular processes, including ion transport, cell signaling, and metabolic regulation. This opens avenues for studying diseases associated with magnesium dysregulation, such as cardiovascular diseases and certain metabolic disorders.

The scientific importance of CNNM1 Gene Knockout Cell Lines cannot be overstated, as they provide invaluable insights into the role of CNNM1 in both normal physiology and disease mechanisms. In research settings, these tools enable the functional characterization of gene targets, contribute to drug discovery efforts by identifying novel therapeutic targets, and facilitate the understanding of genetic interactions in complex biological systems. Clinically, unraveling the nuances of CNNM1 function may pave the way for innovative interventions to address magnesium-related pathologies.

Compared to traditional cell lines or RNA interference approaches, CNNM1 Gene Knockout Cell Lines offer clear advantages. The complete gene knockout provides a more definitive model to elucidate gene function, leading to less ambiguous results. Furthermore, the precision of CRISPR technology ensures high specificity and efficiency, minimizing off-target effects that may confound experimental outcomes.

For researchers and clinicians dedicated to advancing scientific knowledge and improving therapeutic strategies, the integration of CNNM1 Gene Knockout Cell Lines into their workflows holds great promise. This product supports cutting-edge research that can potentially lead to breakthroughs in understanding and treating magnesium-related disorders.

At our company, we pride ourselves on being at the forefront of biotechnological innovation, providing high-quality, rigorously validated biological products that empower scientific discovery. Our expertise in gene editing and cell line development guarantees that CNNM1 Gene Knockout Cell Lines are tailored to meet the precise needs of our users, ensuring robust and reliable experimental results.

Please note that all services are for research use only. Not intended for any clinical use.

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