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CNIH3 Knockout Cell Lines

Gene: CNIH3

Official Full Name: cornichon family AMPA receptor auxiliary protein 3provided by HGNC

Gene Summary: Predicted to enable channel regulator activity and signaling receptor binding activity. Involved in regulation of AMPA receptor activity. Predicted to be located in dendritic shaft and postsynaptic membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in dendrite and glutamatergic synapse. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22898 CNIH3 Knockout cell line (HCT 116) Human CNIH3 1:2~1:4 Negative Online Inquiry
KO22899 CNIH3 Knockout cell line (HEK293) Human CNIH3 1:3~1:6 Negative Online Inquiry

Background

CNIH3 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to lack the expression of the CNIH3 (caprin family member 3) gene. This innovative product serves as a powerful tool in molecular biology and genetic research, allowing scientists to investigate the functional roles of CNIH3 in various biological processes and disease states. By employing CRISPR-Cas9 or other gene-editing techniques, these cell lines enable precise knockout of CNIH3, facilitating the study of its impact on cell signaling, neurodevelopment, and other fundamental processes.

The primary function of CNIH3 Gene Knockout Cell Lines is to provide researchers with a reliable model for understanding how the absence of this gene influences cellular behavior and molecular pathways. As a component involved in the regulation of ion channels and synaptic transmission, CNIH3’s knockout could elucidate its role in neurological disorders or affect pathways related to cellular stress responses. Such insights are critical for researchers aiming to explore therapeutic targets for conditions linked to CNIH3 dysfunction.

The scientific importance of CNIH3 Gene Knockout Cell Lines is underscored by their diverse applications in both basic and translational research. They can be utilized in pharmacological studies to assess the effects of drugs targeting pathways influenced by CNIH3, or in screening experiments to identify compounds that might restore function in cells lacking this gene. In clinical settings, these knockout cells can pave the way for more informed approaches to gene therapy and regenerative medicine.

Compared to alternative models, such as transient knockdown systems or genetic knockouts in whole organisms, CNIH3 Gene Knockout Cell Lines offer notable advantages. They provide a more stable and consistent environment for studying gene function, reduce variability associated with whole-organism models, and can be readily manipulated for high-throughput screening applications. Furthermore, the precise editing capabilities ensure that researchers obtain specific genetic alterations without off-target effects, thereby enhancing the validity of experimental results.

For researchers and clinicians, these knockout cell lines represent a valuable investment in advancing our understanding of complex biological systems. They not only enhance experimental accuracy but also accelerate the journey from bench to bedside in the development of effective therapeutic strategies.

At [Your Company Name], we are committed to providing high-quality biological products that empower scientific discovery. With a focus on innovation and precision, we strive to support the research community in tackling challenging questions in genetic and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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